Document Detail

Oral colonization of Streptococcus mutans in six-month-old predentate infants.
MedLine Citation:
PMID:  11808762     Owner:  NLM     Status:  MEDLINE    
We hypothesize that S. mutans colonization occurs more frequently in pre-term children due to their relative immaturity. In this study of 172 predentate, six-month-old infants, we found that 50% of pre-term and 60% of full-term children harbored S. mutans. The colonization was confirmed by repeat sampling. Although there were minor differences, factors associated with S. mutans infection in pre-term and full-term infants were generally similar. In both groups, increased frequency of sugar was ranked the most important factor (p < 0.001), followed by breast-feeding (p < 0.001), and habits which allowed saliva transfer from mother to infant (p < 0.01). By contrast, non-colonization of S. mutans was associated with multiple courses of antibiotics (p < 0.001). Compared with pre-term children, there were higher percentages of full-term who had night feedings and consumed sugar during sleep times. Mothers with infected infants had S. mutans levels > 5 x 10(5) CFU/mL saliva (p < 0.001), poorer oral hygiene, more periodontal disease, and lower socio-economic status (p < 0.02) and snacked frequently (p < 0.001), compared with mothers with non-infected infants.
A K Wan; W K Seow; D M Purdie; P S Bird; L J Walsh; D I Tudehope
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of dental research     Volume:  80     ISSN:  0022-0345     ISO Abbreviation:  J. Dent. Res.     Publication Date:  2001 Dec 
Date Detail:
Created Date:  2002-01-25     Completed Date:  2002-02-21     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0354343     Medline TA:  J Dent Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2060-5     Citation Subset:  D; IM    
University of Queensland, School of Dentistry, Brisbane, Australia.
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MeSH Terms
Anti-Bacterial Agents / therapeutic use
Bottle Feeding
Breast Feeding
Chi-Square Distribution
Dietary Sucrose / administration & dosage
Infant, Newborn
Infant, Premature
Infectious Disease Transmission, Vertical
Logistic Models
Maternal Welfare
Mouth / microbiology*
Odds Ratio
Statistics, Nonparametric
Streptococcal Infections / transmission*
Streptococcus mutans / isolation & purification*
Sucking Behavior
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Dietary Sucrose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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