Document Detail

Oral clonidine for sedation and analgesia in a burn patient.
MedLine Citation:
PMID:  9793819     Owner:  NLM     Status:  MEDLINE    
Clonidine has both analgesic and sedative actions, and it has been used in a variety of settings as a sedative, or both. We administered oral clonidine with intravenous ketamine to a burn patient to control severe pain. Clonidine produced good analgesia and sedation. In addition, clonidine counterbalanced the sympathetic stimulation of ketamine by virtue of its action in reducing sympathetic outflow. The combination of these two drugs may be useful for burn patients with hypertension or myocardial ischemia.
N Kariya; M Shindoh; S Nishi; H Yukioka; A Asada
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of clinical anesthesia     Volume:  10     ISSN:  0952-8180     ISO Abbreviation:  J Clin Anesth     Publication Date:  1998 Sep 
Date Detail:
Created Date:  1998-12-23     Completed Date:  1998-12-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8812166     Medline TA:  J Clin Anesth     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  514-7     Citation Subset:  IM    
Department of Anesthesiology and Intensive Care Medicine, Osaka City University Medical School, Japan.
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MeSH Terms
Administration, Oral
Analgesics / therapeutic use*
Burns / drug therapy*,  physiopathology
Clonidine / administration & dosage,  therapeutic use*
Hypnotics and Sedatives / therapeutic use*
Ketamine / therapeutic use
Middle Aged
Reg. No./Substance:
0/Analgesics; 0/Hypnotics and Sedatives; 4205-90-7/Clonidine; 6740-88-1/Ketamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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