| Oral clefts: a retrospective study of prevalence and predisposal factors in the State of Mexico. | |
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MedLine Citation:
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PMID: 18587200 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The purpose of this study was to up-date the records concerning oral clefts (OCs) encountered at the Child Hospital of the Maternal Infantile Institute of the State of México, and to examine the association of predisposing factors. A retrospective study of the medical records of patients generated over a 5-year period was carried out. A total of 835 files were reviewed, representing 504 boys and 331 girls. The studied variables were the type of oral clefts and predisposing factors. Kendal correlations at P < or = 0.05 and chi-squared at P < or = 0.05 were used to find any associations between variables. The distribution of oral cleft was: cleft lip and palate (CLP) 70%, cleft palate (CP) 21%, cleft lip (CL) 8%, separate cleft lip and cleft palate 1%. The sex ratios were 1.7 for CLP, 1.7 for CL, and 1 for CP. Municipalities with ethnic groups as well as industrial, agricultural and pottery activities showed a high rate of prevalence. Although there was no significant association with birth weight, familial history of clefting, consanguinity, medication usage during pregnancy, or paternal occupational risk, the results suggested that the most severe clefts were proportionally related to these factors. A significant association with maternal and paternal age, abortion rate, and parity was found. Additionally, maternal agricultural activities suggested that pesticide exposure might be a factor. |
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Authors:
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Blanca S González; María L López; Martha A Rico; Fernando Garduño |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of oral science Volume: 50 ISSN: 1343-4934 ISO Abbreviation: J Oral Sci Publication Date: 2008 Jun |
Date Detail:
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Created Date: 2008-06-30 Completed Date: 2008-10-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9808942 Medline TA: J Oral Sci Country: Japan |
Other Details:
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Languages: eng Pagination: 123-9 Citation Subset: D; IM |
Affiliation:
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Laboratory of Oral Pathology, Research Center, Autonomous University of the State of Mexico. blasgl2001@yahoo.es |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Induced
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statistics & numerical data Adolescent Adult Agriculture / statistics & numerical data Cleft Lip / epidemiology* Cleft Palate / epidemiology* Drug Therapy / statistics & numerical data Ethnic Groups / statistics & numerical data Female Humans Industry / statistics & numerical data Male Maternal Age Maternal Exposure Mexico / epidemiology Middle Aged Occupational Exposure / statistics & numerical data Parity Paternal Age Paternal Exposure Pesticides / adverse effects Pregnancy Prevalence Retrospective Studies Risk Factors Sex Ratio Urban Health / statistics & numerical data |
| Chemical | |
Reg. No./Substance:
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0/Pesticides |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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