Document Detail

Oral challenge test for the diagnosis of gingival hypersensitivity to apple: a case report.
MedLine Citation:
PMID:  16504864     Owner:  NLM     Status:  MEDLINE    
Food intolerance is the term used to describe a hypersensitivity reaction to a food component. These reactions refer to the drug-like side effects caused by a range of chemicals that may be present in food as natural or added components. The range of symptoms which can be induced by food intolerance are very similar to those caused by food allergy, oral allergy syndrome, acute infectious diseases and vesiculobullous disorders; so that on initial presentation, it can be difficult to differentiate between these conditions. A 48-year-old woman with complaints of allergic symptoms was examined with skin prick test (SPT), specific IgE analysis, and oral challenge test for definitive allergen determination. The patient was negative in both specific IgE detection and SPT with commercial extracts of apple, whereas the oral challenge test revealed positive objective symptoms with blister and ulcer formation. Apple has been reported to be the cause of food allergy. To our knowledge, there is no report of apple intolerance in which the lesions are only confined to gingival tissues.
Onur Ozcelik; M Cenk Haytac
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics     Volume:  101     ISSN:  1528-395X     ISO Abbreviation:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod     Publication Date:  2006 Mar 
Date Detail:
Created Date:  2006-02-28     Completed Date:  2006-03-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9508562     Medline TA:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod     Country:  United States    
Other Details:
Languages:  eng     Pagination:  317-21     Citation Subset:  D; IM    
Department of Periodontology, Faculty of Dentistry, Cukurova University, Adana, Turkey.
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MeSH Terms
Food Hypersensitivity / diagnosis*,  etiology
Gingival Diseases / diagnosis*,  etiology
Immunologic Tests
Malus / adverse effects*
Middle Aged
Oral Ulcer / etiology

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