| Oral carcinoma in situ. | |
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MedLine Citation:
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PMID: 1054449 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Oral carcinoma in situ (CIS) as a histopathologic entity was studied in seventy-seven patients to determine the clinical and histologic parameters of the disease. There were forty-nine male and twenty-eight female patients, with 45.1 per cent of the lesions being described clinically as white, 15.9 per cent as red, and 8.5 per cent as a combination of the two. The high-risk sites for CIS were floor of the mouth (23.2 per cent of all lesions), tongue (22.0 per cent), and lips (in males only, 19.5 per cent). Histologically, there was a considerable range of variation in surface keratinization, thickness of epithelium, and certain cytologic alterations. The most consistent of all cytologic changes was loss of orientation of cells. There is no information available concerning possible regression of oral CIS, as is known for CIS of uterine cervix. Furthermore, there is no information concerning the frequency of or the period of transition from oral CIS to invasive carcinoma or whether all oral carcinoma is preceded by CIS. Further studies on this disease are essential. |
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Authors:
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C A Waldron; W G Shafer |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Oral surgery, oral medicine, and oral pathology Volume: 39 ISSN: 0030-4220 ISO Abbreviation: Oral Surg. Oral Med. Oral Pathol. Publication Date: 1975 Feb |
Date Detail:
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Created Date: 1975-05-28 Completed Date: 1975-05-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0376406 Medline TA: Oral Surg Oral Med Oral Pathol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 227-38 Citation Subset: D; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Carcinoma in Situ* / diagnosis, epidemiology, metabolism, pathology Cell Nucleus Color Cytoplasm Epithelial Cells Female Humans Keratins / metabolism Lip Neoplasms / epidemiology Male Middle Aged Mouth Floor Mouth Mucosa Mouth Neoplasms* / diagnosis, metabolism, pathology Palatal Neoplasms / epidemiology Precancerous Conditions Sex Factors Tongue Neoplasms / epidemiology |
| Chemical | |
Reg. No./Substance:
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68238-35-7/Keratins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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