| Oral anticoagulant therapy in the primary and secondary prophylaxis of stroke. | |
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MedLine Citation:
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PMID: 14699705 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Stroke is the first cause of disability and the second cause of mortality in the world. Oral anticoagulants have been proved to be effective in the primary and secondary prophylaxis of stroke not only in cardiac conditions but also in other pathologies such as the antiphospholipid syndrome. Though the efficacy of oral anticoagulants in the prevention of stroke has been consolidated in several conditions such as mechanical prosthesis, atrial fibrillation, and the antiphospholipid syndrome, their role is less clear in patent foramen ovale, interatrial septal aneurysm, dilated cardiomyopathy, and aortic plaques. Nevertheless, oral anticoagulants have recently been re-evaluated in large clinical trials and have been shown to be effective in the secondary prevention of myocardial infarction and stroke. This review considers both the established and controversial aspects and the role of anticoagulation clinics in the practical approach to these patients, as well as their education and quality of life. |
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Authors:
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Cristiana Cauli; Doris Barcellona; Francesco Marongiu |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Italian heart journal : official journal of the Italian Federation of Cardiology Volume: 4 ISSN: 1129-471X ISO Abbreviation: Ital Heart J Publication Date: 2003 Nov |
Date Detail:
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Created Date: 2003-12-31 Completed Date: 2004-04-23 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 100909716 Medline TA: Ital Heart J Country: Italy |
Other Details:
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Languages: eng Pagination: 755-67 Citation Subset: IM |
Affiliation:
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Department of Internal Medical Sciences, University of Cagliari, Cagliari, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Oral Anticoagulants / therapeutic use* Antiphospholipid Syndrome / drug therapy, epidemiology Brain Ischemia / epidemiology, prevention & control Cardiovascular Diseases / drug therapy, epidemiology Europe / epidemiology Humans Incidence Primary Prevention* Risk Factors Stroke / epidemiology, prevention & control* United States / epidemiology |
| Chemical | |
Reg. No./Substance:
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0/Anticoagulants |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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