Document Detail

Oral antibiotics for perforated appendicitis is not recommended.
MedLine Citation:
PMID:  20816017     Owner:  NLM     Status:  MEDLINE    
In the majority of surgical departments in Denmark, the postoperative treatment for acute perforated appendicitis comprises three days of intravenous antibiotics. Recently, it has been proposed that such antibiotic regimen should be replaced by orally administered antibiotics. The aim of this paper was to give an overview of studies on acute perforated appendicitis with postoperative oral antibiotics. Five studies were found in a database search covering the 1966-2009 period. There is no evidence to support a conversion of the postoperative antibiotic regimen from intravenous to oral administration in patients with acute perforated appendicitis.
Mahdi Alamili; Ismail Gögenur; Jacob Rosenberg
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Danish medical bulletin     Volume:  57     ISSN:  1603-9629     ISO Abbreviation:  Dan Med Bull     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-06     Completed Date:  2010-10-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0066040     Medline TA:  Dan Med Bull     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  A4177     Citation Subset:  IM    
Herlev Hospital, Gastroenheden, Denmark.
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MeSH Terms
Administration, Oral
Anti-Bacterial Agents / administration & dosage*,  economics
Antibiotic Prophylaxis* / economics
Appendicitis / therapy*
Infusions, Intravenous
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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