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Oral acyclovir suppression after neonatal herpes.
MedLine Citation:
PMID:  22216852     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
To the Editor: In their study of oral acyclovir in neonates after herpes simplex virus (HSV) infection, Kimberlin et al. (Oct. 6 issue)(1) describe an initial dose of parenteral acyclovir (300 mg per square meter of body-surface area) that is lower than that used in current clinical practice (1500 mg per square meter) administered for 21 days in cases of central nervous system involvement.(2) In addition, the authors do not mention the possible genetic predisposition to HSV among infants with frequent skin relapses(3) and imply that 6 months of oral prophylaxis may be adequate. In our practice, we see two . . .
Authors:
David Bargiela; Hermione Lyall; Leena Mewasingh
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The New England journal of medicine     Volume:  366     ISSN:  1533-4406     ISO Abbreviation:  N. Engl. J. Med.     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-01-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0255562     Medline TA:  N Engl J Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  90-1     Citation Subset:  AIM; IM    
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