Document Detail

Oral alveolar soft part sarcoma in childhood and adolescence: report of two cases and review of literature.
MedLine Citation:
PMID:  22961078     Owner:  NLM     Status:  MEDLINE    
Alveolar soft part sarcoma (ASPS) constitutes a rare soft tissue malignant neoplasm comprising less than 1 % of all soft tissue sarcomas. ASPS demonstrates a strong predilection for adolescents and young adults, with a female predominance reported. The head and neck region is the most commonly affected region in pediatric patients with the tongue and orbit affected most commonly. Herein we present the clinical, radiographic, histopathologic, immunohistochemical and molecular features of two examples of ASPS affecting the oral cavity of 4 and 13 year-old boys, along with a focused review of the literature on intraoral ASPS in pediatric patients.
Prokopios P Argyris; Robyn C Reed; J Carlos Manivel; Dolores Lopez-Terrada; Jared Jakacky; Zuzan Cayci; Konstantinos I Tosios; Stefan E Pambuccian; Lester D R Thompson; Ioannis G Koutlas
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Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2012-09-08
Journal Detail:
Title:  Head and neck pathology     Volume:  7     ISSN:  1936-0568     ISO Abbreviation:  Head Neck Pathol     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-03-15     Completed Date:  2013-08-26     Revised Date:  2013-09-10    
Medline Journal Info:
Nlm Unique ID:  101304010     Medline TA:  Head Neck Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  40-9     Citation Subset:  IM    
Department of Oral Pathology and Medicine, School of Dentistry, National and Kapodistrian University of Athens, Athens, Greece.
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MeSH Terms
Base Sequence
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors / genetics
Child, Preschool
Molecular Sequence Data
Mouth Neoplasms / genetics,  pathology*,  surgery
Oncogene Proteins, Fusion / genetics
Reverse Transcriptase Polymerase Chain Reaction
Sarcoma, Alveolar Soft Part / genetics,  pathology*,  surgery
Reg. No./Substance:
0/ASPSCR1 protein, human; 0/Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; 0/Oncogene Proteins, Fusion; 0/TFE3 protein, human

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