| Optogenetic Strategies to Dissect the Neural Circuits that Underlie Reward and Addiction. | |
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MedLine Citation:
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PMID: 23043156 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Optogenetic strategies for perturbation of neural circuit function have begun to revolutionize systems neuroscience. Whereas optogenetics has proven to be a powerful approach for studying neural systems, the tools to conduct these experiments are still continuously evolving. Here we briefly summarize available hardware and reagents that can be used for studying behaviors related to reward and addiction. In addition, we discuss recent studies in which these strategies have been applied to study neural circuit function in brain slices as well as awake and behaving animals. Collectively, this work serves as a brief introduction to optogenetic techniques and highlights how these tools can be applied to elucidate the neural circuits that underlie reward processing and addiction. |
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Authors:
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Alice M Stamatakis; Garret D Stuber |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-10-6 |
Journal Detail:
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Title: Cold Spring Harbor perspectives in medicine Volume: - ISSN: 2157-1422 ISO Abbreviation: Cold Spring Harb Perspect Med Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-10-8 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101571139 Medline TA: Cold Spring Harb Perspect Med Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Curriculum in Neurobiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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