Document Detail

Options for systemic labor analgesia.
MedLine Citation:
PMID:  17479017     Owner:  NLM     Status:  MEDLINE    
PURPOSE OF REVIEW: This article reviews the challenging practice of systemic analgesia as an alternative to epidural analgesia for labor pain, and places remifentanil within the context of opioid analgesics suitable for managing for labor pain. RECENT FINDINGS: Although systemic opioids have long been used for labor analgesia, they have become less popular because of frequent maternal and neonatal side effects. Recently, their efficacy has been questioned. Patient-controlled intravenous analgesia with fentanyl or sufentanil is currently the method of choice for achieving analgesia during early labor, when epidural analgesia is not feasible. Remifentanil has been suggested as the opioid of choice for labor analgesia, having the advantage of easy administration, predictable pharmacokinetics, and improved neonatal outcomes. The position of remifentanil in obstetric analgesia is now better understood, as reflected by the increasing number of reported studies describing its use. SUMMARY: Remifentanil is now gaining popularity. Remifentanil may be more suitable than other traditional opioids for inducing labor analgesia. Careful monitoring of the parturient and the newborn is recommended, however, to mitigate the potential for maternal and neonatal hypoxemia.
Shmuel Evron; Tiberiu Ezri
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in anaesthesiology     Volume:  20     ISSN:  0952-7907     ISO Abbreviation:  Curr Opin Anaesthesiol     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-05-04     Completed Date:  2007-07-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8813436     Medline TA:  Curr Opin Anaesthesiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  181-5     Citation Subset:  IM    
Department of Anesthesia, Edith Wolfson Medical Center, Holon, affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
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MeSH Terms
Adjuvants, Anesthesia
Analgesia, Obstetrical*
Analgesia, Patient-Controlled
Analgesics, Opioid
Anesthesia, Local
Anesthetics, Intravenous*
Reg. No./Substance:
0/Adjuvants, Anesthesia; 0/Analgesics, Opioid; 0/Anesthetics, Intravenous; 0/Piperidines; 132875-61-7/remifentanil; 437-38-7/Fentanyl; 56030-54-7/Sufentanil; 57-42-1/Meperidine; 71195-58-9/Alfentanil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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