Document Detail

Optimizing scanning phases in detecting small (<2 cm) hepatocellular carcinoma: whole-liver dynamic study with multidetector row CT.
MedLine Citation:
PMID:  18520534     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To define the optimal scanning phases for detecting small hepatocellular carcinomas (HCCs) with whole-liver dynamic helical computed tomography. METHODS: Sixty-one patients with 112 hypervascular HCCs smaller than 2 cm underwent 7-phase dynamic study from the early arterial to the late equilibrium phases of the entire liver. Proof of neoplasms was based on biopsy results and computed tomography with iodized oil. Time-density curves of the individual tumor and the liver were compared. RESULTS: Of 112 hypervascular nodules, the late arterial phase had the best liver-tumor conspicuity (P < 0.001). Ninety-one nodules (81%) had peak liver-tumor contrast in late arterial phase, and only 21 (19%) in the early arterial phase. All the hypervascular HCCs became isoattenuating to the regional parenchyma before the late portal venous phase (120th second). CONCLUSION: The late arterial and late portal venous phases are recommended for detecting small HCC smaller than 2 cm.
Jer-Shyung Huang; Huay-Ben Pan; Chun-Ping Chou; Huei-Lung Liang; Lee-Ren Yeh; Tzong-Long Yang; Shiuh-Inn Liu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of computer assisted tomography     Volume:  32     ISSN:  0363-8715     ISO Abbreviation:  J Comput Assist Tomogr     Publication Date:    2008 May-Jun
Date Detail:
Created Date:  2008-06-03     Completed Date:  2008-06-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7703942     Medline TA:  J Comput Assist Tomogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  341-6     Citation Subset:  IM    
Division of Abdominal Imaging, Department of Radiology, Kaohsiung Veterans General Hospital, 386 Ta-Chung First Road, Kaohsiung, Taiwan.
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MeSH Terms
Carcinoma, Hepatocellular / radiography*
Liver Neoplasms / radiography*
Middle Aged
Prospective Studies
Tomography, X-Ray Computed / methods*

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