| Optimizing the efficacy and safety of oral anticoagulant therapy: high-quality dose management, anticoagulation clinics, and patient self-management. | |
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MedLine Citation:
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PMID: 15199459 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Despite its widespread use, oral anticoagulation therapy suffers from a number of problems that lead to underuse and inadequate treatment. Problems include its narrow therapeutic index, the influence of many concomitant conditions or comorbidities, and the need for high-quality dose management. Poor management of oral anticoagulation is a prime factor influencing the occurrence of adverse events. As a result of these problems, special programs or anticoagulation management services (AMSs) have developed to manage oral anticoagulation. Such programs have demonstrated a significant improvement in outcomes compared with traditional or usual care (UC) by individual physicians. With the introduction of point-of-care prothrombin time monitors, the potential for patient self-testing and self-management has developed. Studies show the possibility of even further improvement in outcomes compared with UC, although the differences from those achieved with an AMS are less impressive. |
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Authors:
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Jack E Ansell |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Seminars in vascular medicine Volume: 3 ISSN: 1528-9648 ISO Abbreviation: Semin Vasc Med Publication Date: 2003 Aug |
Date Detail:
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Created Date: 2004-06-16 Completed Date: 2004-07-15 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 100940307 Medline TA: Semin Vasc Med Country: United States |
Other Details:
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Languages: eng Pagination: 261-70 Citation Subset: IM |
Affiliation:
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Department of Medicine, Boston University Medical Center, Boston, MA, USA. jack.ansell@bmc.org |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Oral Anticoagulants / administration & dosage* Drug Monitoring / methods*, standards Humans Laboratories / standards Prothrombin Time / methods Risk Factors Self Care / methods* Treatment Outcome Warfarin / administration & dosage* |
| Chemical | |
Reg. No./Substance:
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0/Anticoagulants; 81-81-2/Warfarin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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