| Optimizing the arterialized venous flap. | |
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MedLine Citation:
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PMID: 19050520 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Outcome of arterialized venous flaps is quite varied. The authors' initial experiments showed that a good vascular bed contributes significantly to survival of the flap. In continuation of these experiments, this study aimed to understand the influence of architectural variations on flap outcome. METHODS: Fasciocutaneous flaps were designed on the ears of New Zealand rabbits, and the animals were randomized into four groups having flaps that used the larger anterior marginal vein (1.3 mm) or the smaller central vein (0.6 mm) for arterial inflow, with or without isolation of the flap from its bed with a silicone sheet. Flaps were observed for area of flap survival and vasculature was assessed by microangiography. RESULTS: Using the smaller central vein for arterial inflow (n = 15), arterialized venous flaps had an excellent outcome, with good flap survival in 100 percent of the animals (survival of >85 percent of flap area), and a mean flap survival area of 99.4 +/- 1.6 percent. Even when neovascularization was prevented by isolation of the flaps (n = 14), 92 percent of central vein flaps showed good survival, with a mean flap survival area of 93.3 +/- 7.3 percent, which was significantly better than that of anterior marginal vein flaps (n = 22), which showed good flap survival in only 27 percent of the animals (mean flap survival area, 76.4 +/- 12.1 percent). CONCLUSIONS: Survival of arterialized venous flaps is optimized by using smaller-caliber veins for inflow and reserving larger-caliber veins for outflow. This regulates inflow and avoids high blood pressure, and arterialized venous flaps behave as physiologic flaps do, by not relying on neovascularization for survival. |
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Authors:
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Brigitte Pittet; Pierre Quinodoz; Navid Alizadeh; Kai-Uwe Schlaudraff; Ajay L Mahajan |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Plastic and reconstructive surgery Volume: 122 ISSN: 1529-4242 ISO Abbreviation: Plast. Reconstr. Surg. Publication Date: 2008 Dec |
Date Detail:
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Created Date: 2008-12-03 Completed Date: 2009-01-07 Revised Date: 2011-02-16 |
Medline Journal Info:
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Nlm Unique ID: 1306050 Medline TA: Plast Reconstr Surg Country: United States |
Other Details:
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Languages: eng Pagination: 1681-9 Citation Subset: AIM; IM |
Affiliation:
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Department of Plastic and Reconstructive Surgery, University Hospitals of Geneva, Geneva, Switzerland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Angiography Animals Arteries / physiology, surgery Arteriovenous Shunt, Surgical / methods* Ear, External / blood supply*, surgery* Microcirculation / physiology Models, Animal Neovascularization, Physiologic / physiology Rabbits Regional Blood Flow / physiology* Surgical Flaps / blood supply* Veins / physiology, surgery |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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