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Optimizing SHIELD-HIT for carbon ion treatment.
MedLine Citation:
PMID:  22469994     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The SHIELD-HIT Monte Carlo transport code has been widely used in particle therapy, but has previously shown some discrepancies, when compared with experimental data. In this work, the inelastic nuclear cross sections of SHIELD-HIT are calibrated to experimental data for carbon ions. In addition, the models for nuclear fragmentation were adjusted to experiments, for the partial charge-changing cross section of carbon ions in water. Comparison with fragmentation yield experiments for carbon and neon primaries were made for validation. For carbon primaries, excellent agreement between simulation and experiment was observed, with only minor discrepancies. For neon primaries, the agreement was also good, but larger discrepancies were observed, which require further investigation. In conclusion, the current version SHIELD-HIT10A is well suited for simulating problems arising in particle therapy for clinical ion beams.
Authors:
David C Hansen; Armin Lühr; Nikolai Sobolevsky; Niels Bassler
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-4-02
Journal Detail:
Title:  Physics in medicine and biology     Volume:  57     ISSN:  1361-6560     ISO Abbreviation:  -     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-4-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401220     Medline TA:  Phys Med Biol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  2393-2409     Citation Subset:  -    
Affiliation:
Department of Experimental Clinical Oncology, Aarhus University Hospital, Nørrebrogade 44 Bldg 5, DK-8000 Aarhus C, Denmark. Department of Physics and Astronomy, Aarhus University, Ny Munkegade 120, DK-8000 Aarhus C, Denmark.
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