| Optimization and scale-up of propionic acid production by propionic acid-tolerant Propionibacterium acidipropionici with glycerol as the carbon source. | |
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MedLine Citation:
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PMID: 20620054 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Propionic acid production by Propionibacterium acidipropionici with glycerol as sole carbon source was studied in 7-L batch and 10m(3) bioreactor cultures. In batch cultures, propionic acid production increased and specific cell growth rate decreased with increasing glycerol concentrations. Maximum propionic acid production and productivity reached 44.62+/-1.12g/L and 0.20+/-0.0075gL(-1)h(-1)at 220h, respectively, when glycerol was fed at a constant rate of 0.01L/h from 72 to 120h with an initial glycerol concentration of 30g/L. In the 10m(3) bioreactor, maximum propionic acid production reached 47.28+/-0.12g/L at 240h. This glycerol feeding approach may be useful for propionic acid production on an industrial scale. |
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Authors:
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Yunfeng Zhu; Jianghua Li; Ming Tan; Long Liu; Lili Jiang; Jun Sun; Pengsoon Lee; Guocheng Du; Jian Chen |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Bioresource technology Volume: 101 ISSN: 1873-2976 ISO Abbreviation: Bioresour. Technol. Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-08-02 Completed Date: 2011-01-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9889523 Medline TA: Bioresour Technol Country: England |
Other Details:
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Languages: eng Pagination: 8902-6 Citation Subset: IM |
Affiliation:
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Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi, China. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Actinomycetales
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drug effects,
metabolism* Carbon / metabolism Glycerol / metabolism* Pilot Projects Propionic Acids / isolation & purification, metabolism*, pharmacology |
| Chemical | |
Reg. No./Substance:
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0/Propionic Acids; 56-81-5/Glycerol; 7440-44-0/Carbon; 79-09-4/propionic acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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