Document Detail

Optimization of perfusion imaging for acute cerebral ischemia: review of recent clinical trials and recommendations for future studies.
MedLine Citation:
PMID:  18806174     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The use of thrombolytic agents and other forms of reperfusion therapy has provided a means to reverse ischemia and minimize the size of infarctions. The purpose of this review is to examine various clinical trials of reperfusion agents and address key imaging issues.
CONCLUSION: Advanced MRI and CT play a growing role in selection of patients for therapy. Numerous clinical trials have shed light on the efficacy of various reperfusion therapies; disparities in trial design have also left unanswered questions.
James M Provenzale; Max Wintermark
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  AJR. American journal of roentgenology     Volume:  191     ISSN:  1546-3141     ISO Abbreviation:  AJR Am J Roentgenol     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-09-22     Completed Date:  2008-10-16     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  7708173     Medline TA:  AJR Am J Roentgenol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1263-70     Citation Subset:  AIM; IM    
Department of Radiology, Duke University Medical Center, Box 3808, Durham, NC 27710, USA.
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MeSH Terms
Acute Disease
Brain Ischemia / diagnosis*,  radiography
Clinical Trials as Topic
Magnetic Resonance Imaging / methods*
Tomography, X-Ray Computed / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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