Document Detail

Optimization of the culture medium for growth and the kinetics of lactate fermentation by Pediococcus sp. ISK-1.
MedLine Citation:
PMID:  9145518     Owner:  NLM     Status:  MEDLINE    
The growth of a newly isolated strain of Pediococcus sp., designated ISK-1, was very slow and the concentration of cells in the medium remained low. Fermentation with an initial 30 g/liter glucose required about 60 h. To stimulate fermentation, we attempted to optimize the medium by flask culture and jar fermentation tests. Mevalonic acid and mieki (soy bean hydrolyzate) stimulated fermentation and increased the rate of formation of DL-lactate. Kinetic analysis of the fermentation showed that mevalonic acid markedly increased the specific glucose consumption rate and the specific lactate production rate. Mieki and mevalonic acid had a synergistic effect, but the effect of mevalonic acid was different from that of mieki.
E Herawati; A Ishizaki
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bioscience, biotechnology, and biochemistry     Volume:  61     ISSN:  0916-8451     ISO Abbreviation:  Biosci. Biotechnol. Biochem.     Publication Date:  1997 Apr 
Date Detail:
Created Date:  1997-06-03     Completed Date:  1997-06-03     Revised Date:  2000-12-18    
Medline Journal Info:
Nlm Unique ID:  9205717     Medline TA:  Biosci Biotechnol Biochem     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  604-8     Citation Subset:  B    
Department of Food Science and Technology, Faculty of Agriculture, Kyushu University, Fukuoka, Japan.
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MeSH Terms
Cell Division / drug effects
Culture Media
Lactic Acid / metabolism*
Mevalonic Acid / pharmacology
Pediococcus / cytology,  drug effects,  metabolism*
Reg. No./Substance:
0/Culture Media; 150-97-0/Mevalonic Acid; 50-21-5/Lactic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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