Document Detail

Optimization of repolarization during biventricular pacing: a new target in patients with biventricular devices?
MedLine Citation:
PMID:  20146780     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Evaluation of repolarization during sequentional biventricular pacing. METHODS: Patients with biventricular devices, and left ventricular leads placed to the basal part of lateral left ventricular wall were enrolled. QRS, QTc, JTc, and corrected Tpeak-Tend intervals were compared during sequentional biventricular, left ventricular, and right ventricular pacing. RESULTS: Five patients with nonischemic and five with ischemic cardiomyopathy due to anterior myocardial infarction were enrolled. No correlation was observed between values of repolarization among patients. The optimal values of repolarization were significantly different from values of echocardiographically guided hemodynamic optimization. Two patients with biventricular pacing-induced ventricular fibrillation were successfully treated by reprogramming of V-V delay according to interventricular delay resulting in shorter Tpeak-Tend interval, although delayed effect of amiodarone in one of these patients cannot be ruled out. CONCLUSIONS: Patients with biventricular devices may be prone to development of ventricular arrhythmias depending on programmed V-V interval. We suggest that optimization of repolarization may be performed in patients with biventricular pacemakers in the absence of backup ICD and those with frequent episodes of ventricular tachyarrhythmias, although this finding deserves further study.
Cengizhan T?rko?lu; Farid Aliyev; Cengiz Celiker; G?khan Cetin; G?khan Alici; I?il Uzunhasan; Inci Firatli
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc     Volume:  15     ISSN:  1542-474X     ISO Abbreviation:  Ann Noninvasive Electrocardiol     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-02-11     Completed Date:  2010-05-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9607443     Medline TA:  Ann Noninvasive Electrocardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  36-42     Citation Subset:  IM    
Istanbul University, Institute of Cardiology, Department of Cardiology, Division of Pacing and Electrophysiology, Istanbul, Turkey.
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MeSH Terms
Arrhythmias, Cardiac / diagnosis,  etiology*
Cardiomyopathy, Dilated / therapy
Electrocardiography / methods,  statistics & numerical data
Myocardial Ischemia / therapy
Pacemaker, Artificial / adverse effects*
Signal Processing, Computer-Assisted
Treatment Outcome
Ventricular Fibrillation / diagnosis,  etiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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