| Optimising thrombolytic therapy in elderly patients with acute myocardial infarction. | |
| | |
MedLine Citation:
|
PMID: 8785464 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The incidence of myocardial infarction (MI) and its subsequent mortality increases with age. However, elderly patients are less likely to receive thrombolytic therapy. Among other reasons, this may be because elderly patients with evolving MI often have atypical signs and symptoms and delay their presentation for medical treatment by 2 hours compared with younger patients. The risk of (most often fatal) cerebral bleeding in elderly patients treated with aspirin, heparin and thrombolytic drugs is about 1 to 2 per 1000 patients, and is 2 times higher than in younger patients. In order to decrease the incidence of intracranial haemorrhage in elderly patients with acute MI, thrombolytic treatment should not be recommended in patients at increased risk of cerebral bleeding. Otherwise, the benefit of thrombolytic treatment outweigh the risk; for every 1000 elderly patients treated with thrombolytic drugs, approximately 36 are saved compared with those receiving control treatment. |
| | |
Authors:
|
M Verstraete; D Collen |
Related Documents
:
|
3819264 - Extracorporeal shock wave lithotripsy for the treatment of urinary calculi in the elderly. 15858184 - Respiratory syncytial virus infection in elderly and high-risk adults. 7264124 - Hyperparathyroidism in the elderly. 15565164 - Outcome of acute promyelocytic leukemia treated with all trans retinoic acid and chemot... 7149564 - Survey of patients' responses to breast reconstruction. 2595324 - Intestinal absorption of oxalate and calcium in patients with jejunoileal bypass. |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Drugs & aging Volume: 8 ISSN: 1170-229X ISO Abbreviation: Drugs Aging Publication Date: 1996 Jan |
Date Detail:
|
Created Date: 1996-09-26 Completed Date: 1996-09-26 Revised Date: 2005-11-16 |
Medline Journal Info:
|
Nlm Unique ID: 9102074 Medline TA: Drugs Aging Country: NEW ZEALAND |
Other Details:
|
Languages: eng Pagination: 17-22 Citation Subset: IM |
Affiliation:
|
Center for Molecular and Vascular Biology, University of Leuven, Belgium. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged* Humans Middle Aged Myocardial Infarction / drug therapy*, mortality Risk Factors Thrombolytic Therapy* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Treatment of photoaged skin. Efficacy, tolerability and costs of available agents.
Next Document: Quality of life in older patients with congestive heart failure. Effects of ACE inhibitors.