| Optimal timing of post-treatment [18F]fluorodeoxyglucose-PET/CT for patients with head and neck malignancy. | |
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MedLine Citation:
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PMID: 23196675 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVES: The aims of this study were to evaluate the ability of [F]fluorodeoxyglucose (F-FDG)-PET/computed tomography (CT) to identify tumor recurrence, nodal metastases, and distant metastases for surveillance and discuss the optimal timing of F-FDG-PET/CT examination after the completion of treatment for head and neck malignancy. METHODS: A total of 319 patients who underwent a post-treatment F-FDG-PET/CT examination for head and neck malignancy were studied. F-FDG-PET/CT findings were compared with the final diagnosis confirmed by histopathological examinations or clinical and radiological follow-up for at least 6 months. Patients were divided into two groups according to the presence or absence of clinical suspicion of recurrent disease. The diagnostic accuracy of F-FDG-PET/CT was analyzed for each group. Patients were also categorized according to the time interval between the completion of treatment and the post-treatment F-FDG-PET/CT examination. Differences in diagnostic accuracy due to the time interval were also evaluated. RESULTS: The diagnostic accuracy of F-FDG-PET/CT was high for both groups. The overall accuracy of F-FDG-PET/CT performed within 2 months (69%) after the completion of treatment was significantly inferior to that performed after 2 months (93%). CONCLUSION: F-FDG-PET should be performed immediately for patients with clinically suspected recurrent disease. In others, it should be performed at later than 2 months after the completion of the treatment. |
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Authors:
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Shin Nakamura; Akira Toriihara; Kiyoshi Okochi; Hiroshi Watanabe; Hitoshi Shibuya; Tohru Kurabayashi |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-11-27 |
Journal Detail:
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Title: Nuclear medicine communications Volume: - ISSN: 1473-5628 ISO Abbreviation: Nucl Med Commun Publication Date: 2012 Nov |
Date Detail:
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Created Date: 2012-11-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8201017 Medline TA: Nucl Med Commun Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Departments of aOral and Maxillofacial Radiology bDiagnostic Radiology and Oncology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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