| Optimal pharmacological stress testing for the diagnosis of coronary artery disease: a probabilistic approach. | |
MedLine Citation:
|
PMID: 8869117 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Previous reports have suggested that dobutamine stress echocardiography compares favourably with other stress agent-imaging modality combinations for the detection of coronary artery disease. However, in daily clinical practice the value of a test is defined on a probability basis. To study the relative diagnostic contribution of clinical and dobutamine stress test variables, Bayesian analysis was performed in 223 patients with suspected coronary artery disease, who underwent coronary angiography and a high-dose dobutamine stress test in conjunction with electrocardiography, echocardiography and Technetium-99m sestamibi SPECT myocardial perfusion scintigraphy. According to the pre-test (clinical) probabilities, patients were divided into low-, intermediate- and high-risk groups; 155 patients were in the intermediate-risk group. After dobutamine stress echocardiography the number of patients in this intermediate-risk group was reduced to 102 (P < 0.0001). This reduction of patients in the intermediate-risk group by echocardiography was better than perfusion scintigraphy (102 vs 126 patients, P < 0.05) or classic markers of ischaemia such as angina and/or ST-segment changes (102 vs 150, P < 0.0001). Moreover, there was a good correlation between the echocardiographic post-test probabilities and the true distribution of coronary artery disease. |
Authors:
|
M L Geleijnse; T H Marwick; E Boersma; J W Deckers; J A Melin; P M Fioretti |
Related Documents
:
|
8896927 - Lung-heart ratio in stress thallium myocardial perfusion imaging in patients with a his... 11773927 - Assessment of cardiac viability by thallium 201 redistribution and dobutamine echocardi... 11175117 - Effects of low-dose dobutamine on displacement of the atrioventricular plane and assess... 19962857 - Quantitative analysis of function and perfusion during dobutamine stress in the detecti... 22721657 - Contemporary incidence and predictors of stent thrombosis and other major adverse cardi... 24643467 - Interaction between selenium and mercury in biological samples of pakistani myocardial ... |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: European heart journal Volume: 16 Suppl M ISSN: 0195-668X ISO Abbreviation: Eur. Heart J. Publication Date: 1995 Nov |
Date Detail:
|
Created Date: 1997-01-03 Completed Date: 1997-01-03 Revised Date: 2005-11-16 |
Medline Journal Info:
|
Nlm Unique ID: 8006263 Medline TA: Eur Heart J Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 3-10 Citation Subset: IM |
Affiliation:
|
Thoraxcenter and Department of Nuclear Medicine, Erasmus University Rotterdam, Netherlands. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Coronary Disease / diagnosis* Diagnostic Imaging Dobutamine / diagnostic use* Female Humans Male Middle Aged Probability Stimulation, Chemical |
| Chemical | |
Reg. No./Substance:
|
34368-04-2/Dobutamine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Pharmacological agents for stress testing in the diagnosis of coronary artery disease.
Next Document: Functional evaluation of patients with coronary artery disease: selection of appropriate pharmacolog...