| Optimal pacing modes after cardiac transplantation: is synchronisation of recipient and donor atria beneficial? | |
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MedLine Citation:
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PMID: 1389737 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To investigate the response of the transplanted heart to different pacing modes and to synchronisation of the recipient and donor atria in terms of cardiac output at rest. DESIGN: Doppler derived cardiac output measurements at three pacing rates (90/min, 110/min and 130/min) in five pacing modes: right ventricular pacing, donor atrial pacing, recipient-donor synchronous pacing, donor atrial-ventricular sequential pacing, and synchronous recipient-donor atrial-ventricular sequential pacing. PATIENTS: 11 healthy cardiac transplant recipients with three pairs of epicardial leads inserted at transplantation. RESULTS: Donor atrial pacing (+11% overall) and donor atrial-ventricular sequential pacing (+8% overall) were significantly better than right ventricular pacing (p < 0.001) at all pacing rates. Synchronised pacing of recipient and donor atrial segments did not confer additional benefit in either atrial or atrial-ventricular sequential modes of pacing in terms of cardiac output at rest at these fixed rates. CONCLUSIONS: Atrial pacing or atrial-ventricular sequential pacing appear to be appropriate modes in cardiac transplant recipients. Synchronisation of recipient and donor atrial segments in this study produced no additional benefit. Chronotropic competence in these patients may, however, result in improved exercise capacity and deserves further investigation. |
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Authors:
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G Parry; K Malbut; J H Dark; R S Bexton |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: British heart journal Volume: 68 ISSN: 0007-0769 ISO Abbreviation: Br Heart J Publication Date: 1992 Aug |
Date Detail:
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Created Date: 1992-11-18 Completed Date: 1992-11-18 Revised Date: 2010-09-07 |
Medline Journal Info:
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Nlm Unique ID: 0370634 Medline TA: Br Heart J Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 195-8 Citation Subset: AIM; IM |
Affiliation:
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Department of Cardiology, Freeman Hospital, Newcastle upon Tyne. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Atrial Function / physiology* Cardiac Output / physiology Cardiac Pacing, Artificial / methods* Female Heart / physiopathology Heart Transplantation / physiology* Humans Male Middle Aged |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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