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Optimal oxygen saturation in premature infants.
MedLine Citation:
PMID:  22232627     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
There is a delicate balance between too little and too much supplemental oxygen exposure in premature infants. Since underuse and overuse of supplemental oxygen can harm premature infants, oxygen saturation levels must be monitored and kept at less than 95% to prevent reactive oxygen species-related diseases, such as retinopathy of prematurity and bronchopulmonary dysplasia. At the same time, desaturation below 80 to 85% must be avoided to prevent adverse consequences, such as cerebral palsy. It is still unclear what range of oxygen saturation is appropriate for premature infants; however, until the results of further studies are available, a reasonable target for pulse oxygen saturation (SpO(2)) is 90 to 93% with an intermittent review of the correlation between SpO(2) and the partial pressure of arterial oxygen tension (PaO(2)). Because optimal oxygenation depends on individuals at the bedside making ongoing adjustments, each unit must define an optimal target range and set alarm limits according to their own equipment or conditions. All staff must be aware of these values and adjust the concentration of supplemental oxygen frequently.
Authors:
Meayoung Chang
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Publication Detail:
Type:  Journal Article     Date:  2011-09-30
Journal Detail:
Title:  Korean journal of pediatrics     Volume:  54     ISSN:  2092-7258     ISO Abbreviation:  Korean J Pediatr     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2012-01-10     Completed Date:  2012-10-02     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101215374     Medline TA:  Korean J Pediatr     Country:  Korea (South)    
Other Details:
Languages:  eng     Pagination:  359-62     Citation Subset:  -    
Affiliation:
Department of Pediatrics, Chungnam National University School of Medicine, Daejeon, Korea.
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