Document Detail

Optimal outcome in individuals with a history of autism.
MedLine Citation:
PMID:  23320807     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Although autism spectrum disorders (ASDs) are generally considered lifelong disabilities, literature suggests that a minority of individuals with an ASD will lose the diagnosis. However, the existence of this phenomenon, as well as its frequency and interpretation, is still controversial: were they misdiagnosed initially, is this a rare event, did they lose the full diagnosis, but still suffer significant social and communication impairments or did they lose all symptoms of ASD and function socially within the normal range?
METHODS: The present study documents a group of these optimal outcome individuals (OO group, n=34) by comparing their functioning on standardized measures to age, sex, and nonverbal IQ matched individuals with high-functioning autism (HFA group, n=44) or typical development (TD group, n=34). For this study, 'optimal outcome' requires losing all symptoms of ASD in addition to the diagnosis, and functioning within the nonautistic range of social interaction and communication. Domains explored include language, face recognition, socialization, communication, and autism symptoms.
RESULTS: Optimal outcome and TD groups' mean scores did not differ on socialization, communication, face recognition, or most language subscales, although three OO individuals showed below-average scores on face recognition. Early in their development, the OO group displayed milder symptoms than the HFA group in the social domain, but had equally severe difficulties with communication and repetitive behaviors.
CONCLUSIONS: Although possible deficits in more subtle aspects of social interaction or cognition are not ruled out, the results substantiate the possibility of OO from autism spectrum disorders and demonstrate an overall level of functioning within normal limits for this group.
Deborah Fein; Marianne Barton; Inge-Marie Eigsti; Elizabeth Kelley; Letitia Naigles; Robert T Schultz; Michael Stevens; Molly Helt; Alyssa Orinstein; Michael Rosenthal; Eva Troyb; Katherine Tyson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of child psychology and psychiatry, and allied disciplines     Volume:  54     ISSN:  1469-7610     ISO Abbreviation:  J Child Psychol Psychiatry     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-16     Completed Date:  2013-07-12     Revised Date:  2014-02-04    
Medline Journal Info:
Nlm Unique ID:  0375361     Medline TA:  J Child Psychol Psychiatry     Country:  England    
Other Details:
Languages:  eng     Pagination:  195-205     Citation Subset:  IM    
Copyright Information:
© 2013 The Authors. Journal of Child Psychology and Psychiatry © 2013 Association for Child and Adolescent Mental Health.
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MeSH Terms
Age Factors
Autistic Disorder / psychology*
Interview, Psychological
Psychiatric Status Rating Scales
Psychological Tests
Remission, Spontaneous
Sex Factors
Wechsler Scales
Young Adult
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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