| Optimal myocardial preservation: cooling, cardioplegia, and conditioning. | |
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MedLine Citation:
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PMID: 8572815 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Myocardial preservation techniques have evolved in conjunction with cardiac surgery and currently offer substantial protection against myocardial injury. We propose that cardiac preconditioning, a robust, endogenous mechanism of cardioprotection, is emerging as an important adjunct to current cardioplegic techniques. By reviewing the physiologic basis for current cardioplegic strategies, and understanding the cardioprotective benefits of preconditioning, we postulate that cardiac preconditioning may represent an important, clinically accessible component of myocardial protection. |
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Authors:
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J C Cleveland; D R Meldrum; R T Rowland; A Banerjee; A H Harken |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
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Title: The Annals of thoracic surgery Volume: 61 ISSN: 0003-4975 ISO Abbreviation: Ann. Thorac. Surg. Publication Date: 1996 Feb |
Date Detail:
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Created Date: 1996-03-06 Completed Date: 1996-03-06 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 15030100R Medline TA: Ann Thorac Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 760-8 Citation Subset: AIM; IM |
Affiliation:
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Department of Surgery, University of Colorado Health Sciences Center, Denver 80262, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cardiac Surgical Procedures / methods* Energy Metabolism / physiology Heart* Heart Arrest, Induced / methods Homeostasis / physiology Humans Hypothermia, Induced Intraoperative Care Myocardial Ischemia / prevention & control* Myocardium / metabolism Organ Preservation / methods* Perfusion / methods |
| Grant Support | |
ID/Acronym/Agency:
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GM 08315/GM/NIGMS NIH HHS; HL-43696/HL/NHLBI NIH HHS; HL-44186/HL/NHLBI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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