| Optimal k-space sampling for dynamic contrast-enhanced MRI with an application to MR renography. | |
| | |
MedLine Citation:
|
PMID: 19230014 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
For time-resolved acquisitions with k-space undersampling, a simulation method was developed for selecting imaging parameters based on minimization of errors in signal intensity versus time and physiologic parameters derived from tracer kinetic analysis. Optimization was performed for time-resolved angiography with stochastic trajectories (TWIST) algorithm applied to contrast-enhanced MR renography. A realistic 4D phantom comprised of aorta and two kidneys, one healthy and one diseased, was created with ideal tissue time-enhancement pattern generated using a three-compartment model with fixed parameters, including glomerular filtration rate (GFR) and renal plasma flow (RPF). TWIST acquisitions with different combinations of sampled central and peripheral k-space portions were applied to this phantom. Acquisition performance was assessed by the difference between simulated signal intensity (SI) and calculated GFR and RPF and their ideal values. Sampling of the 20% of the center and 1/5 of the periphery of k-space in phase-encoding plane and data-sharing of the remaining 4/5 minimized the errors in SI (<5%), RPF, and GFR (both <10% for both healthy and diseased kidneys). High-quality dynamic human images were acquired with optimal TWIST parameters and 2.4 sec temporal resolution. The proposed method can be generalized to other dynamic contrast-enhanced MRI applications, e.g., MR angiography or cancer imaging. |
| | |
Authors:
|
Ting Song; Andrew F Laine; Qun Chen; Henry Rusinek; Louisa Bokacheva; Ruth P Lim; Gerhard Laub; Randall Kroeker; Vivian S Lee |
Related Documents
:
|
2002114 - Proximal interruption of a main pulmonary artery with transpleural collateral vessels: ... 21340734 - Magnetic resonance imaging of anatomical variants of the subtalar joint. 18270714 - Contrast-enhanced magnetic resonance imaging of the breast: the value of pharmacokineti... 12450104 - Cervical carcinoma with full-thickness stromal invasion: efficacy of dynamic mr imaging... 15324364 - Mri and csf studies in the early diagnosis of alzheimer's disease. 10488874 - Mechanical instability as a cause of gait disturbance in high-grade spondylolisthesis: ... |
Publication Detail:
|
Type: Evaluation Studies; Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
|
Title: Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine Volume: 61 ISSN: 1522-2594 ISO Abbreviation: Magn Reson Med Publication Date: 2009 May |
Date Detail:
|
Created Date: 2009-05-25 Completed Date: 2009-07-27 Revised Date: 2011-01-07 |
Medline Journal Info:
|
Nlm Unique ID: 8505245 Medline TA: Magn Reson Med Country: United States |
Other Details:
|
Languages: eng Pagination: 1242-8 Citation Subset: IM |
Copyright Information:
|
(c) 2009 Wiley-Liss, Inc. |
Affiliation:
|
Department of Radiology, New York University School of Medicine, New York, New York 10016, USA. songting@gmail.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Algorithms* Contrast Media Female Gadolinium DTPA / diagnostic use* Humans Hypertension, Renal / diagnosis* Image Enhancement / methods Image Interpretation, Computer-Assisted / methods* Imaging, Three-Dimensional / methods* Kidney / pathology* Magnetic Resonance Imaging / instrumentation, methods* Phantoms, Imaging Radioisotope Renography / methods Reproducibility of Results Sensitivity and Specificity |
| Grant Support | |
ID/Acronym/Agency:
|
R01 DK063183/DK/NIDDK NIH HHS; R01 DK063183-05/DK/NIDDK NIH HHS; R01 DK067523/DK/NIDDK NIH HHS; R01 DK067523-05/DK/NIDDK NIH HHS |
| Chemical | |
Reg. No./Substance:
|
0/Contrast Media; 80529-93-7/Gadolinium DTPA |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Improving non-contrast-enhanced steady-state free precession angiography with compressed sensing.
Next Document: Radial sliding-window magnetic resonance angiography (MRA) with highly-constrained projection recons...