Document Detail


Optimal iodine dose for 3-dimensional multidetector-row CT angiography of the liver.
MedLine Citation:
PMID:  21708439     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
PURPOSE: To clarify the optimal iodine dose of contrast material for 3-dimensional multidetector-row CT angiography (3D-MDCTA) of the venous vasculature of the liver using volume rendering technique. MATERIALS AND METHODS: This study included 103 patients who were randomly assigned to 5 contrast-enhanced MDCT protocol groups with different body-weight-tailored doses of contrast material: 500, 600, 630, 650, and 700mgI/kg body weight. The arterial, portal, and hepatic parenchymal phases were obtained to evaluate enhancement values of the aorta, portal vein, and hepatic vein. Visualization of the portal and hepatic veins on the volume-rendering images of 3D-MDCTA was evaluated using a 5-point grade. Dunnett's test was used to compare the mean enhancement value and mean grades of image quality (700mgI/kg dose group was control). RESULTS: The mean enhancement values of portal and hepatic vein in the group with 500 and 600mgI/kg were significantly lower than those of the control group. During visual assessment, a significantly lower mean grades were observed in 500mgI/kg groups for the portal vein, and 500 and 600mgI/kg groups for hepatic vein. There were no significant intergroup differences in mean enhancement values and visual assessment among the groups using 630mgI/kg or more. CONCLUSION: Iodine doses of 630mgI/kg was recommended for 3D-MDCTA.
Authors:
Tomoaki Ichikawa; Utaroh Motosugi; Hiroyuki Morisaka; Hironobu Sou; Kojiro Onohara; Katsuhiro Sano; Tsutomu Araki
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-6-25
Journal Detail:
Title:  European journal of radiology     Volume:  -     ISSN:  1872-7727     ISO Abbreviation:  -     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-6-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8106411     Medline TA:  Eur J Radiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.
Affiliation:
Department of Radiology, University of Yamanashi, Yamanashi, Japan.
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