Document Detail


Optimal interval between middle cerebral artery velocity measurements when monitoring pregnancies complicated by red cell alloimmunization.
MedLine Citation:
PMID:  16354970     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To evaluate the optimal interval between middle cerebral artery (MCA) Doppler measurements when monitoring pregnancies complicated by red cell alloimmunization. METHODS: Thirty-nine fetal blood samplings (FBS) performed on 24 pregnant women with red blood cell alloimmunization followed up using both MCA peak systolic velocity and time-averaged mean velocity measurements on weekly basis. RESULTS: In total, 65.5 and 37.5% of women with moderate or severe fetal anemia had abnormal MCA Doppler values 1 and 2 weeks, respectively, before FBS was performed. CONCLUSIONS: A weekly assessment of women at risk for fetal anemia is optimal in most of the cases even though 35.5% of cases of moderate or severe fetal anemia are expected to have normal Doppler measurements the week before the decision of doing an FBS is made.
Authors:
Jose L Bartha; Sherif A Abdel-Fattah; Alyson Hunter; Mark Denbow; Phillipa Kyle; Peter W Soothill
Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  Fetal diagnosis and therapy     Volume:  21     ISSN:  1015-3837     ISO Abbreviation:  Fetal. Diagn. Ther.     Publication Date:  2006  
Date Detail:
Created Date:  2005-12-15     Completed Date:  2006-01-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9107463     Medline TA:  Fetal Diagn Ther     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  22-5     Citation Subset:  IM    
Copyright Information:
(c) 2006 S. Karger AG, Basel
Affiliation:
Fetal Medicine Research Unit, Department of Obstetrics and Gynaecology, St. Michael's Hospital, University of Bristol, Bristol, UK. joseluis.bartha@uca.es
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MeSH Terms
Descriptor/Qualifier:
Adult
Anemia / etiology,  physiopathology,  ultrasonography*
Blood Flow Velocity
Female
Fetal Diseases / etiology,  physiopathology,  ultrasonography*
Humans
Infant, Newborn
Middle Cerebral Artery / physiopathology,  ultrasonography*
Pregnancy
Rh Isoimmunization / complications*
Time Factors
Ultrasonography, Doppler
Ultrasonography, Prenatal*

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