| Optimal inhalation procedure for the fenoterol powder inhaler. | |
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MedLine Citation:
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PMID: 6581057 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To assess the optimal inhalation procedure of a fenoterol (Berotec) powder inhaler, the degree of reversibility of lung function impairment was studied in 10 patients with stable asthma after 1) deposition of 0.2 mg fenoterol under the tongue, 2) a rapid inhalation from residual volume (RV) to total lung capacity (TLC), and 3) a slow inhalation from functional residual capacity (FRC) to TLC. There was no effect on FEV1 of depositing fenoterol under the tongue, but both inhalation menoeuvres improved FEV1 significantly (p less than 0.01) and the rapid inspiration manoeuvre even slightly more (p less than 0.05) than the slow. It is concluded that the problem of impaction of large particles in the mouth and pharynx following rapid inhalation from a conventional pressurized cannister is considerably reduced with the fenoterol powder inhaler, due to the resistance it causes which tend to automatically reduce a forced inspiration flow rate to optimal low values. |
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Authors:
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S Groth; H Dirksen |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: European journal of respiratory diseases. Supplement Volume: 130 ISSN: 0106-4347 ISO Abbreviation: Eur J Respir Dis Suppl Publication Date: 1983 |
Date Detail:
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Created Date: 1984-02-14 Completed Date: 1984-02-14 Revised Date: 2008-02-21 |
Medline Journal Info:
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Nlm Unique ID: 8010618 Medline TA: Eur J Respir Dis Suppl Country: DENMARK |
Other Details:
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Languages: eng Pagination: 17-24 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Asthma / drug therapy*, physiopathology Ethanolamines / administration & dosage* Female Fenoterol / administration & dosage* Forced Expiratory Volume Humans Male Middle Aged Powders Vital Capacity |
| Chemical | |
Reg. No./Substance:
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0/Ethanolamines; 0/Powders; 13392-18-2/Fenoterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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