Document Detail

Optimal inhalation procedure for the fenoterol powder inhaler.
MedLine Citation:
PMID:  6581057     Owner:  NLM     Status:  MEDLINE    
To assess the optimal inhalation procedure of a fenoterol (Berotec) powder inhaler, the degree of reversibility of lung function impairment was studied in 10 patients with stable asthma after 1) deposition of 0.2 mg fenoterol under the tongue, 2) a rapid inhalation from residual volume (RV) to total lung capacity (TLC), and 3) a slow inhalation from functional residual capacity (FRC) to TLC. There was no effect on FEV1 of depositing fenoterol under the tongue, but both inhalation menoeuvres improved FEV1 significantly (p less than 0.01) and the rapid inspiration manoeuvre even slightly more (p less than 0.05) than the slow. It is concluded that the problem of impaction of large particles in the mouth and pharynx following rapid inhalation from a conventional pressurized cannister is considerably reduced with the fenoterol powder inhaler, due to the resistance it causes which tend to automatically reduce a forced inspiration flow rate to optimal low values.
S Groth; H Dirksen
Related Documents :
10830177 - Effectiveness of the fold plication method in lung volume reduction surgery.
3146677 - Maximal expiratory flow in the guinea pig.
2759977 - Measurement of alveolar pressure in closed-chest dogs during flow interruption.
6501027 - Mean airway pressure and alveolar pressure during high-frequency ventilation.
10349677 - Long-term renal function in primary hypertension. an epidemiological and pathophysiolog...
2681407 - Optimal size of cuff bladder for indirect measurement of arterial pressure in adults.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of respiratory diseases. Supplement     Volume:  130     ISSN:  0106-4347     ISO Abbreviation:  Eur J Respir Dis Suppl     Publication Date:  1983  
Date Detail:
Created Date:  1984-02-14     Completed Date:  1984-02-14     Revised Date:  2008-02-21    
Medline Journal Info:
Nlm Unique ID:  8010618     Medline TA:  Eur J Respir Dis Suppl     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  17-24     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Asthma / drug therapy*,  physiopathology
Ethanolamines / administration & dosage*
Fenoterol / administration & dosage*
Forced Expiratory Volume
Middle Aged
Vital Capacity
Reg. No./Substance:
0/Ethanolamines; 0/Powders; 13392-18-2/Fenoterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Patient errors and preference with regard to the use of a bronchodilating spray and fenoterol (Berot...
Next Document:  Acceptance of fenoterol powder for inhalation in children with bronchial asthma.