Document Detail


Optimal inhalation procedure for the fenoterol powder inhaler.
MedLine Citation:
PMID:  6581057     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To assess the optimal inhalation procedure of a fenoterol (Berotec) powder inhaler, the degree of reversibility of lung function impairment was studied in 10 patients with stable asthma after 1) deposition of 0.2 mg fenoterol under the tongue, 2) a rapid inhalation from residual volume (RV) to total lung capacity (TLC), and 3) a slow inhalation from functional residual capacity (FRC) to TLC. There was no effect on FEV1 of depositing fenoterol under the tongue, but both inhalation menoeuvres improved FEV1 significantly (p less than 0.01) and the rapid inspiration manoeuvre even slightly more (p less than 0.05) than the slow. It is concluded that the problem of impaction of large particles in the mouth and pharynx following rapid inhalation from a conventional pressurized cannister is considerably reduced with the fenoterol powder inhaler, due to the resistance it causes which tend to automatically reduce a forced inspiration flow rate to optimal low values.
Authors:
S Groth; H Dirksen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of respiratory diseases. Supplement     Volume:  130     ISSN:  0106-4347     ISO Abbreviation:  Eur J Respir Dis Suppl     Publication Date:  1983  
Date Detail:
Created Date:  1984-02-14     Completed Date:  1984-02-14     Revised Date:  2008-02-21    
Medline Journal Info:
Nlm Unique ID:  8010618     Medline TA:  Eur J Respir Dis Suppl     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  17-24     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Asthma / drug therapy*,  physiopathology
Ethanolamines / administration & dosage*
Female
Fenoterol / administration & dosage*
Forced Expiratory Volume
Humans
Male
Middle Aged
Powders
Vital Capacity
Chemical
Reg. No./Substance:
0/Ethanolamines; 0/Powders; 13392-18-2/Fenoterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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