Document Detail


Optimal hematocrit for hemodialysis.
MedLine Citation:
PMID:  9375264     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Considerable controversy continues over the optimal hematocrit target for dialysis patients being treated with recombinant erythropoietin. Recent short-term studies have demonstrated a significant improvement in brain function when hematocrit is 42% compared with when it is 31%. Questions regarding the safety of long-term maintenance of a normal hematocrit have been raised; however, this is in part because of the early termination of the Normal Hematocrit Cardiac Trial, in which there was an increased occurrence of death or nonfatal myocardial infarction in patients randomly assigned to the normal hematocrit group. For the present, a target hematocrit of 36% seems reasonable and safe.
Authors:
A R Nissenson
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in nephrology and hypertension     Volume:  6     ISSN:  1062-4821     ISO Abbreviation:  Curr. Opin. Nephrol. Hypertens.     Publication Date:  1997 Nov 
Date Detail:
Created Date:  1998-01-14     Completed Date:  1998-01-14     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9303753     Medline TA:  Curr Opin Nephrol Hypertens     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  524-7     Citation Subset:  IM    
Affiliation:
UCLA Medical Center 90095, USA.
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MeSH Terms
Descriptor/Qualifier:
Hematocrit*
Humans
Renal Dialysis / standards*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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