Document Detail

Optimal endexpiratory airway pressure for ventilated patients.
MedLine Citation:
PMID:  7035518     Owner:  NLM     Status:  MEDLINE    
In patients ventilated for acute respiratory failure PEEP was changed either by gradual increase and decrease (5 cm H2O/min) or in steps of 5 cm H2O. The effects on gas exchange, pulmonary mechanics and pulmonary and systemic circulation were studied. Total compliance did not change uniformly and cardiac index decreased so much due to PEEP that the increase in PaO2 could not prevent the decrease of arterial oxygen transport. No variable was found helpful to predict the "best PEEP" in a clinical situation.
G Wolff; H Langenstein; R Schwendener; P Lischer
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Intensive care medicine     Volume:  8     ISSN:  0342-4642     ISO Abbreviation:  Intensive Care Med     Publication Date:  1982 Jan 
Date Detail:
Created Date:  1982-04-12     Completed Date:  1982-04-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7704851     Medline TA:  Intensive Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  39-48     Citation Subset:  IM    
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MeSH Terms
Blood Circulation
Intermittent Positive-Pressure Ventilation / methods*
Positive-Pressure Respiration / methods*
Pulmonary Circulation
Pulmonary Wedge Pressure
Respiratory Insufficiency / therapy*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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