| Optimal dose of lignocaine for preventing pain on injection of propofol. | |
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MedLine Citation:
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PMID: 2015149 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The purpose of this study was to define the optimum dose of lignocaine required to reduce pain on injection of propofol. We conducted a prospective, randomized, double-blind trial on 310 patients undergoing anaesthesia. Patients were allocated to four groups according to the lignocaine dosage: group A (control), no lignocaine; group B, lignocaine 0.1 mg kg-1; group C, lignocaine 0.2 mg kg-1; group D, lignocaine 0.4 mg kg-1. Our results showed that a dose of lignocaine 0.1 mg kg-1 significantly reduced the incidence of pain and that there was no improvement when the dose was increased. |
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Authors:
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G Gehan; P Karoubi; F Quinet; A Leroy; C Rathat; J L Pourriat |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: British journal of anaesthesia Volume: 66 ISSN: 0007-0912 ISO Abbreviation: Br J Anaesth Publication Date: 1991 Mar |
Date Detail:
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Created Date: 1991-05-17 Completed Date: 1991-05-17 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372541 Medline TA: Br J Anaesth Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 324-6 Citation Subset: IM |
Affiliation:
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Département d'Anesthésie-Réanimation, CHU Avicenne-Jean Verdier, Université Paris XIII, Bobigny, France. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Anesthesia, Intravenous / adverse effects* Double-Blind Method Female Humans Lidocaine / administration & dosage* Male Middle Aged Pain / chemically induced, prevention & control* Propofol / adverse effects* Prospective Studies |
| Chemical | |
Reg. No./Substance:
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137-58-6/Lidocaine; 2078-54-8/Propofol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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