| Optimal dietary approaches for prevention of type 2 diabetes: a life-course perspective. | |
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MedLine Citation:
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PMID: 20049415 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In recent years, several alternative dietary approaches, including high-protein and low-glycaemic-load diets, have produced faster rates of weight loss than traditional low-fat, high-carbohydrate diets. These diets share an under-recognised unifying mechanism: the reduction of postprandial glycaemia and insulinaemia. Similarly, some food patterns and specific foods (potatoes, white bread, soft drinks) characterised by hyperglycaemia are associated with higher risk of adiposity and type 2 diabetes. Profound compensatory hyperinsulinaemia, exacerbated by overweight, occurs during critical periods of physiological insulin resistance such as pregnancy and puberty. The dramatic rise in gestational diabetes and type 2 diabetes in the young may therefore be traced to food patterns that exaggerate postprandial glycaemia and insulinaemia. The dietary strategy with the strongest evidence of being able to prevent type 2 diabetes is not the accepted low-fat, high-carbohydrate diet, but alternative dietary approaches that reduce postprandial glycaemia and insulinaemia without adversely affecting other risk factors. |
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Authors:
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A E Buyken; P Mitchell; A Ceriello; J Brand-Miller |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review Date: 2010-01-05 |
Journal Detail:
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Title: Diabetologia Volume: 53 ISSN: 1432-0428 ISO Abbreviation: Diabetologia Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-02-03 Completed Date: 2010-10-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0006777 Medline TA: Diabetologia Country: Germany |
Other Details:
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Languages: eng Pagination: 406-18 Citation Subset: IM |
Affiliation:
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Nutrition and Health Unit, Research Institute of Child Nutrition, Heinstück 11, 44225 Dortmund, Germany. buyken@fke-do.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adipose Tissue
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metabolism Carbohydrates / chemistry Diabetes Mellitus, Type 2 / diet therapy*, prevention & control* Diet Glucose / metabolism Homeostasis Humans Hyperglycemia / drug therapy, metabolism Insulin Resistance Obesity / complications Research Design Risk Risk Factors |
| Chemical | |
Reg. No./Substance:
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0/Carbohydrates; 50-99-7/Glucose |
| Comments/Corrections | |
Comment In:
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Diabetologia. 2010 Aug;53(8):1809-10
[PMID:
20454774
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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