| Optimal contrast medium injection protocols for the depiction of the Adamkiewicz artery using 64-detector CT angiography. | |
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MedLine Citation:
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PMID: 18625352 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: To determine the optimal contrast medium injection protocol for demonstrating the Adamkiewicz artery (AKA) using 64-detector CT angiography (CTA). MATERIALS AND METHODS: CTA was performed using 64-detector CT. The study population consisted of 80 patients (mean age 67.2 years) with aortoiliac diseases. In the first 60 patients 540 mg I/kg body weight was administered over 25s. The patients were randomly assigned to three protocols with imaging started at 15 (protocol A-1), 18 (A-2), or 21s (A-3) after triggering (threshold 150 HU). The other 20 received 720 mg I/kg body weight with an imaging delay of 18s (protocol B). Two radiologists evaluated the presence of the AKA and measured the attenuation of the aorta and AKA. RESULTS: Aortic enhancement was 360.4, 348, 279.3, and 372 HU for protocols A-1, A-2, A-3, and B, respectively. There was no significant difference between the A-1 and A-2 protocols (Tukey-Kramer test, p=0.73); however, aortic enhancement was significantly lower in A-3 than A-1 and A-2 (p<0.01). There was no significant difference between A-2 and B (p=0.40). AKA attenuation was 69.3, 91.9, 94.6, and 105.4 HU for protocols A-1, A-2, A-3, and B, respectively. There was no significant difference between the A-2 and A-3 protocols (p=0.91); however, AKA attenuation was significantly lower with A-1 than A-2 or A-3 (p=0.01). AKA attenuation was significantly lower with A-2 than B (p=0.03) and there was a significant difference between A-2 (50%) and B (95%) in the depiction of the hairpin configuration of the AKA (p=0.02). CONCLUSION: For the demonstration of the AKA at CTA, the optimal protocol used an imaging delay of 18s after triggering and an iodine dose of 720 mg I/kg body weight. |
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Authors:
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Y Nakayama; K Awai; Y Yanaga; T Nakaura; Y Funama; T Hirai; Y Yamashita |
Publication Detail:
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Type: Journal Article; Randomized Controlled Trial Date: 2008-04-14 |
Journal Detail:
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Title: Clinical radiology Volume: 63 ISSN: 1365-229X ISO Abbreviation: Clin Radiol Publication Date: 2008 Aug |
Date Detail:
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Created Date: 2008-07-15 Completed Date: 2008-10-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 1306016 Medline TA: Clin Radiol Country: England |
Other Details:
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Languages: eng Pagination: 880-7 Citation Subset: IM |
Affiliation:
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Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Angiography / methods Aortic Aneurysm / radiography Aortography / methods* Contrast Media / administration & dosage* Drug Administration Schedule Female Humans Iohexol / administration & dosage*, diagnostic use Lumbar Vertebrae Male Middle Aged Spinal Cord / blood supply* Thoracic Vertebrae Time Factors Tomography, X-Ray Computed / methods |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 66108-95-0/Iohexol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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