Document Detail


Optimal contrast medium injection protocols for the depiction of the Adamkiewicz artery using 64-detector CT angiography.
MedLine Citation:
PMID:  18625352     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: To determine the optimal contrast medium injection protocol for demonstrating the Adamkiewicz artery (AKA) using 64-detector CT angiography (CTA). MATERIALS AND METHODS: CTA was performed using 64-detector CT. The study population consisted of 80 patients (mean age 67.2 years) with aortoiliac diseases. In the first 60 patients 540 mg I/kg body weight was administered over 25s. The patients were randomly assigned to three protocols with imaging started at 15 (protocol A-1), 18 (A-2), or 21s (A-3) after triggering (threshold 150 HU). The other 20 received 720 mg I/kg body weight with an imaging delay of 18s (protocol B). Two radiologists evaluated the presence of the AKA and measured the attenuation of the aorta and AKA. RESULTS: Aortic enhancement was 360.4, 348, 279.3, and 372 HU for protocols A-1, A-2, A-3, and B, respectively. There was no significant difference between the A-1 and A-2 protocols (Tukey-Kramer test, p=0.73); however, aortic enhancement was significantly lower in A-3 than A-1 and A-2 (p<0.01). There was no significant difference between A-2 and B (p=0.40). AKA attenuation was 69.3, 91.9, 94.6, and 105.4 HU for protocols A-1, A-2, A-3, and B, respectively. There was no significant difference between the A-2 and A-3 protocols (p=0.91); however, AKA attenuation was significantly lower with A-1 than A-2 or A-3 (p=0.01). AKA attenuation was significantly lower with A-2 than B (p=0.03) and there was a significant difference between A-2 (50%) and B (95%) in the depiction of the hairpin configuration of the AKA (p=0.02). CONCLUSION: For the demonstration of the AKA at CTA, the optimal protocol used an imaging delay of 18s after triggering and an iodine dose of 720 mg I/kg body weight.
Authors:
Y Nakayama; K Awai; Y Yanaga; T Nakaura; Y Funama; T Hirai; Y Yamashita
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial     Date:  2008-04-14
Journal Detail:
Title:  Clinical radiology     Volume:  63     ISSN:  1365-229X     ISO Abbreviation:  Clin Radiol     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-07-15     Completed Date:  2008-10-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  1306016     Medline TA:  Clin Radiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  880-7     Citation Subset:  IM    
Affiliation:
Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Angiography / methods
Aortic Aneurysm / radiography
Aortography / methods*
Contrast Media / administration & dosage*
Drug Administration Schedule
Female
Humans
Iohexol / administration & dosage*,  diagnostic use
Lumbar Vertebrae
Male
Middle Aged
Spinal Cord / blood supply*
Thoracic Vertebrae
Time Factors
Tomography, X-Ray Computed / methods
Chemical
Reg. No./Substance:
0/Contrast Media; 66108-95-0/Iohexol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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