| Optimal T2-weighted MR cholangiopancreatographic images can be obtained after administration of gadoxetic acid. | |
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MedLine Citation:
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PMID: 20656837 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To compare the image quality and diagnostic performance with T2-weighted magnetic resonance (MR) cholangiopancreatographic images obtained before and after dynamic MR imaging performed with gadoxetic acid. MATERIALS AND METHODS: This retrospective study was approved by the institutional review board, and informed consent was waived. Fifty-six patients suspected of having pancreatic or biliary disease underwent two-dimensional (2D) single-section and three-dimensional (3D) multisection MR cholangiopancreatography before and after dynamic imaging with gadoxetic acid. One radiologist measured the mean signal-to-noise ratios (SNRs) and contrast-to-noise ratios (CNRs) of the common bile duct on precontrast and postcontrast images. Two radiologists independently reviewed the 2D and 3D MR cholangiopancreatographic images in random order. The depiction of each segment of the pancreaticobiliary duct, the presence of artifacts, background suppression, and overall image quality were assessed according to a four-point scale. Paired t, McNemar, and Wilcoxon signed rank tests were performed with a power analysis. Interobserver agreement was assessed by using the kappa statistic. RESULTS: Mean SNRs at precontrast MR imaging (2D, 50.8 +/- 45.1 [standard deviation]; 3D, 54.7 +/- 25.5) were similar to those at postcontrast MR imaging (2D, 48.5 +/- 45.7; 3D, 51.5 +/- 21.6). Mean CNRs were also similar between precontrast and postcontrast MR imaging (2D, 45.5 +/- 43.0 vs 44.2 +/- 45.2; 3D, 51.4 +/- 24.3 vs 48.7 +/- 21.0). Depiction scores for each segment of the pancreaticobiliary duct were also similar between 2D and 3D precontrast and postcontrast images. Both radiologists found that scores for background suppression were improved on postcontrast 2D MR images (3.79 and 3.84) compared with precontrast images (3.25 and 3.64). One of the two radiologists found that scores for artifacts (precontrast, 1.23; postcontrast, 1.09) and for overall image quality (precontrast, 3.54; postcontrast, 3.71) were improved at 2D postcontrast MR cholangiopancreatography. CONCLUSION: Both 2D and 3D MR cholangiopancreatography can be effectively performed immediately after gadoxetic acid-enhanced dynamic MR imaging in patients suspected of having biliary or pancreatic disease. |
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Authors:
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Kyung Ah Kim; Myeong-Jin Kim; Mi-Suk Park; Joon Seok Lim; Jin-Young Choi; Hye-Suk Hong; Ki Whang Kim |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Radiology Volume: 256 ISSN: 1527-1315 ISO Abbreviation: Radiology Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-07-26 Completed Date: 2010-09-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: United States |
Other Details:
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Languages: eng Pagination: 475-84 Citation Subset: AIM; IM |
Affiliation:
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Department of Radiology and Institute of Gastroenterology, Brain Korea 21 Project, Yonsei University College of Medicine, Shinchon-dong 134, Seodaemun-ku, Seoul 120-752, Republic of Korea. |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Biliary Tract Diseases / diagnosis* Cholangiopancreatography, Magnetic Resonance / methods* Contrast Media / administration & dosage Female Gadolinium DTPA / administration & dosage*, diagnostic use* Humans Image Enhancement / methods* Male Middle Aged Pancreatic Diseases / diagnosis* Reproducibility of Results Sensitivity and Specificity Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/gadolinium ethoxybenzyl DTPA; 80529-93-7/Gadolinium DTPA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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