| Optimal MRI methods for direct stereotactic targeting of the subthalamic nucleus and globus pallidus. | |
| | |
MedLine Citation:
|
PMID: 20652256 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
OBJECTIVE: Reliable identification of the subthalamic nucleus (STN) and globus pallidus interna (GPi) is critical for deep brain stimulation (DBS) of these structures. The purpose of this study was to compare the visibility of the STN and GPi with various MRI techniques and to assess the suitability of each technique for direct stereotactic targeting. METHODS: MR images were acquired from nine volunteers with T2- and proton density-weighted (PD-W) fast spin echo, susceptibility-weighted imaging (SWI), phase-sensitive inversion recovery and quantitative T1, T2 and T2* mapping sequences. Contrast-to-noise ratios (CNR) for the STN and GPi were calculated for all sequences. Targeting errors on SWI were evaluated on magnetic susceptibility maps. The sequences demonstrating the best conspicuity of DBS target structures (SWI and T2*) were then applied to ten patients with movement disorders, and the CNRs for these techniques were assessed. RESULTS: SWI offers the highest CNR for the STN, but standard PD-W images provide the best CNR for the pallidum. Susceptibility maps indicated that the GPi margins may be shifted slightly on SWI, although no shifts were seen for the STN. CONCLUSION: SWI may improve the visibility of the STN on pre-operative MRI, potentially improving the accuracy of direct stereotactic targeting. |
| | |
Authors:
|
Ruth L O'Gorman; Karin Shmueli; Keyoumars Ashkan; Michael Samuel; David J Lythgoe; Asal Shahidiani; Stephen J Wastling; Michelle Footman; Richard P Selway; Jozef Jarosz |
Related Documents
:
|
15066296 - Effects of geometric distortion in 0.2t mri on radiotherapy treatment planning of prost... 22006756 - The application of magnetic resonance imaging in preoperative evaluation of patients wi... 21656376 - Visualization support for the planning of hepatic needle placement. 21839176 - Atypical language lateralisation associated with right fronto-temporal grey matter incr... 9127046 - Carotid artery stenosis: optimization of ct angiography with a combination of shaded su... 16798706 - Coccidioidomycosis with cerebral and cerebellar granulomas. |
Publication Detail:
|
Type: Journal Article Date: 2010-07-21 |
Journal Detail:
|
Title: European radiology Volume: 21 ISSN: 1432-1084 ISO Abbreviation: Eur Radiol Publication Date: 2011 Jan |
Date Detail:
|
Created Date: 2010-12-02 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9114774 Medline TA: Eur Radiol Country: Germany |
Other Details:
|
Languages: eng Pagination: 130-6 Citation Subset: IM |
Affiliation:
|
Department of Neuroradiology, King's College Hospital, Denmark Hill, London, SE5 9RS, UK. ruth.ogorman@kcl.ac.uk |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: 64-row MDCT perfusion of head and neck squamous cell carcinoma: technical feasibility and quantitati...
Next Document: Hyperintense acute reperfusion marker on FLAIR is not associated with early haemorrhagic transformat...