Document Detail


Optical imaging of visually guided reaching in macaque posterior parietal cortex.
MedLine Citation:
PMID:  23392845     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Sensorimotor transformation for reaching movements in primates requires a large network of visual, parietal, and frontal cortical areas. We performed intrinsic optical imaging over posterior parietal cortex including areas 7a and the dorsal perilunate in macaque monkeys during visually guided hand movements. Reaching was performed while foveating one of nine static reach targets; thus eye-position-varied concurrently with reach position. The hemodynamic reflectance signal was analyzed during specific phases of the task including pre-reach, reach, and touch epochs. The eye position maps changed substantially as the task progressed: First, direction of spatial tuning shifted from a weak preference close to the center to the lower eye positions in both cortical areas. Overall tuning strength was greater in area 7a. Second, strength of spatial tuning increased from the early pre-reach to the later touch epoch. These consistent temporal changes suggest that dynamic properties of the reflectance signal were modulated by task parameters. The peak amplitude and peak delay of the reflectance signal showed considerable differences between eye position but were similar between areas. Compared with a detection task using a lever response, the reach task yielded higher amplitudes and longer delays. These findings demonstrate a spatially tuned topographical representation for reaching in both areas and suggest a strong synergistic combination of various feedback signals that result in a spatially tuned amplification of the hemodynamic response in posterior parietal cortex.
Authors:
Barbara Heider; Ralph M Siegel
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-2-8
Journal Detail:
Title:  Brain structure & function     Volume:  -     ISSN:  1863-2661     ISO Abbreviation:  Brain Struct Funct     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-2-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101282001     Medline TA:  Brain Struct Funct     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, 197 University Avenue, Newark, NJ, 07102, USA, barbara@cortex.rutgers.edu.
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