| Optical coherence tomography of peripheral retinal lesions in enucleated human eye specimens with histologic correlation II. | |
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MedLine Citation:
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PMID: 17169843 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To report optical coherence tomography (OCT)-histologic correlations of two peripheral retinal lesions (PRLs) and to emphasize the feasibility of OCT imaging in fixed tissue specimens. METHODS: We studied seven formalin-fixed human eyes two of which contained two common peripheral retinal lesions. OCT scans were performed through these lesions and the vitreous base area, and the images were correlated with corresponding histologic sections. RESULTS: Two PRLs including a retinal break and pars plana cysts in addition to the pars plicata and anterior vitreous were successfully imaged. Their optical characteristics correlated well with histology. OCT findings that may help differentiate the hyaloid face and vitreous skirt were also observed. CONCLUSIONS: The correlation between OCT images and corresponding histologic sections demonstrates the feasibility of OCT imaging in fixed tissue specimens. Optical characteristics of the vitreous noted in this study may be helpful in understanding disease processes involving the vitreomacular interface. |
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Authors:
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Nicola G Ghazi; Robert M Knape |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Current eye research Volume: 31 ISSN: 0271-3683 ISO Abbreviation: Curr. Eye Res. Publication Date: 2006 Dec |
Date Detail:
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Created Date: 2006-12-15 Completed Date: 2007-01-23 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8104312 Medline TA: Curr Eye Res Country: England |
Other Details:
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Languages: eng Pagination: 1047-9 Citation Subset: IM |
Affiliation:
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Department of Ophthalmology, University of Virginia Health System, Charlottesville, Virginia 22908, USA. ngg6f@virginia.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Eye Enucleation Humans Macular Edema / diagnosis* Retina / pathology* Retinal Perforations / diagnosis* Tissue Fixation Tomography, Optical Coherence / methods* Vitreous Body / pathology* |
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