Document Detail

Optical coherence tomography in dermatology.
MedLine Citation:
PMID:  23314617     Owner:  NLM     Status:  MEDLINE    
Optical coherence tomography (OCT) is a noninvasive diagnostic method that offers a view into the superficial layers of the skin in vivo in real-time. An infrared broadband light source allows the investigation of skin architecture and changes up to a depth of 1 to 2 mm with a resolution between 15 and 3 μm, depending on the system used. Thus OCT enables evaluation of skin lesions, especially nonmelanoma skin cancers and inflammatory diseases, quantification of skin changes, visualization of parasitic infestations, and examination of other indications such as the investigation of nails. OCT provides a quick and useful diagnostic imaging technique for a number of clinical questions and is a valuable addition or complement to other noninvasive imaging tools such as dermoscopy, high-frequency ultrasound, and confocal laser scan microscopy.
Elke Sattler; Raphaela Kästle; Julia Welzel
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Publication Detail:
Type:  Comparative Study; Journal Article; Review    
Journal Detail:
Title:  Journal of biomedical optics     Volume:  18     ISSN:  1560-2281     ISO Abbreviation:  J Biomed Opt     Publication Date:  2013 Jun 
Date Detail:
Created Date:  2013-01-14     Completed Date:  2013-06-06     Revised Date:  2013-08-06    
Medline Journal Info:
Nlm Unique ID:  9605853     Medline TA:  J Biomed Opt     Country:  United States    
Other Details:
Languages:  eng     Pagination:  061224     Citation Subset:  IM    
Ludwig-Maximilian University of Munich, Department of Dermatology and Allergology, Germany.
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MeSH Terms
Carcinoma, Basal Cell / diagnosis
Dermatology / methods*
Dermoscopy / methods
Keratosis, Actinic / diagnosis
Luminescent Measurements
Melanoma / diagnosis
Microscopy, Confocal
Optical Phenomena
Skin / anatomy & histology,  pathology
Skin Diseases / diagnosis*
Skin Neoplasms / diagnosis
Tomography, Optical Coherence / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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