Document Detail


Optical Coherence Tomography evaluation in X-linked retinoschisis.
MedLine Citation:
PMID:  23138727     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
X-linked Retinoschisis is a bilateral retinal disease with a recessive X-linked inheritance, characterized by a macular involvement. Maculopathy consists of bilateral star-shaped microcystic changes. Peripheral retina is sometimes involved with schisis. In two years, were examined 10 eyes of 5 male patients (age range 20-25 years old) with X-linked Juvenile Retinoschisis and progressive reduction of visual acuity. Macular alterations were classified as: Typical foveal schisis; Altered foveal reflection; Lines of pigmentary demarcation; Retinal pigmentary epithelium atrophy; Hole in retinal internal layer. OCT images showed a separation of neurosensorial retina that coincided with classical histopathological findings. Examination results were correlated with clinical examination and compared with ERG findings. OCT images underline an increase of retinal thickness with a separation in the nerve fiber layer in the foveal space.
Authors:
D Domanico; M Nebbioso; S Fragiotta; G Belcaro; E M Vingolo
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-09
Journal Detail:
Title:  Panminerva medica     Volume:  -     ISSN:  1827-1898     ISO Abbreviation:  Panminerva Med     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0421110     Medline TA:  Panminerva Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
University Sapienza of Rome, S.M. Goretti Hospital, Latina, Italy - marcella.nebbioso@uniroma1.it.
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