Document Detail


Optical coherence tomography and ultrasound biomicroscopy imaging of opaque corneas.
MedLine Citation:
PMID:  23073488     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: The purpose was to determine the interchangeability of ultrasound biomicroscopy (UBM) and anterior segment optical coherence tomography (AS-OCT) for corneal opacity depth measurement.
METHODS: Twenty-six eyes of 26 consecutive patients with corneal opacities were examined by both AS-OCT and UBM. The corneal thickness and the corneal opacity depth were measured and compared. The interchangeability was determined by Bland-Altman plotting.
RESULTS: The difference in the full corneal thickness and in the corneal opacity depth between OCT and UBM was 5 ± 7 μm and -1 ± 8 μm, respectively. There were strong correlations and no significant differences between the paired parameters (all r > 0.99, P < 0.01). The limits of agreement were 5 ± 14 μm for the corneal thickness and -1 ± 14.8 μm for the corneal opacity depth.
CONCLUSIONS: AS-OCT and UBM may be used interchangeably for measuring both full corneal thickness and corneal opacity depth in patients with corneal opacity.
Authors:
Shi-you Zhou; Chun-xiao Wang; Xiao-yu Cai; David Huang; Yi-zhi Liu
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cornea     Volume:  32     ISSN:  1536-4798     ISO Abbreviation:  Cornea     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-03-08     Completed Date:  2013-09-05     Revised Date:  2014-04-22    
Medline Journal Info:
Nlm Unique ID:  8216186     Medline TA:  Cornea     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e25-30     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Corneal Opacity / diagnosis*
Corneal Stroma / pathology
Female
Humans
Male
Microscopy, Acoustic*
Middle Aged
Prospective Studies
Reproducibility of Results
Tomography, Optical Coherence*
Young Adult
Grant Support
ID/Acronym/Agency:
EY018184/EY/NEI NIH HHS; R01 EY018184/EY/NEI NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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