| Optical coherence tomography for complete management of patients with diabetic retinopathy. | |
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MedLine Citation:
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PMID: 20522019 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Diabetic retinopathy is a major complication of patients with diabetes mellitus and can lead to a decrease in vision. The precise mechanisms leading to the development of diabetic retinopathy and the progressive decrease of vision are still undetermined. Recent studies have shown that not only vascular but also neuronal abnormalities are associated with the pathogenesis of diabetic retinopathy. Because neuronal cell death leads to an irreversible decrease in visual function, early changes in the morphology and physiology of the neural retinas of diabetic patients are important. The alterations of the morphology of the retina can be obtained by high-resolution B-scan optical coherence tomography (OCT). The thickness of the macular area and retinal nerve fiber layer can be measured reliably and accurately by the installed software of OCT instruments. The high-resolution images can be used to evaluate diabetic macular edema and optic nerve damage quantitatively in patients with diabetic retinopathy. This review describes how the OCT measurements can be used to manage patients with diabetic retinopathy. We also present the early retinal changes involved in the pathogenesis of diabetic retinopathy. |
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Authors:
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Toshiyuki Oshitari; Yoshinori Mitamura |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Current diabetes reviews Volume: 6 ISSN: 1875-6417 ISO Abbreviation: Curr Diabetes Rev Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-07-12 Completed Date: 2010-10-29 Revised Date: 2011-07-08 |
Medline Journal Info:
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Nlm Unique ID: 101253260 Medline TA: Curr Diabetes Rev Country: United Arab Emirates |
Other Details:
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Languages: eng Pagination: 207-14 Citation Subset: IM |
Affiliation:
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Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, Inohana 1-8-1, Chuo-ku, Chiba 260-8670, Chiba, Japan. Tarii@aol.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Diabetic Retinopathy
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pathology,
physiopathology,
therapy* Humans Image Interpretation, Computer-Assisted / methods Macular Edema / etiology, pathology, radiography Models, Biological Optic Nerve / pathology, radiography Organ Size Remission Induction / methods Retina / pathology, radiography Tomography, Optical Coherence* / methods, utilization Visual Acuity / physiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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