| Optic neuropathy of Graves disease: results of transantral orbital decompression and long-term follow-up in 215 patients. | |
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MedLine Citation:
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PMID: 12967795 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To review demographic characteristics, clinical features, and long-term outcomes of patients with optic neuropathy of Graves disease after transantral orbital decompression. DESIGN: Retrospective analysis of noncomparative interventional case series; long-term follow-up by questionnaire. METHODS: Medical record data (preoperative and postoperative assessments) were collected from patients who had transantral orbital decompression to treat Graves optic neuropathy. Responses to two follow-up questionnaires concerning patient satisfaction were evaluated. Statistical analysis (reflected as P values) compared preoperative and early postoperative (< or =182 days) data. RESULTS: Between November 1969 and May 1989, 215 patients underwent transantral orbital decompression for Graves optic neuropathy. In 205 eyes with visual acuity of 20/40 or worse before decompression, visual acuity improved by 3 Snellen lines or more in 110 (54%) (P <.001). Of 291 eyes with visual field defects preoperatively, 120 (41%) had resolution, and 126 (43%) had improvement postoperatively (P <.001). Proptosis was reduced in 350 eyes by 4.4 +/- 2.3 mm (mean +/- SD) (P <.001). In 104 eyes, disk edema resolved in 72 (69%) and improved in 28 (27%). Responses to questionnaires mailed in 1990 and 2000 showed that 76% and 88% of respondents, respectively, were subjectively satisfied with the results of orbital decompression. CONCLUSIONS: Transantral orbital decompression appeared to be effective in treating optic neuropathy of Graves disease. Patient satisfaction was high at 10-year and 20-year follow-up. |
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Authors:
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Cacia V Soares-Welch; Vahab Fatourechi; George B Bartley; Charles W Beatty; Colum A Gorman; Rebecca S Bahn; Erik J Bergstralh; Cathy D Schleck; James A Garrity |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: American journal of ophthalmology Volume: 136 ISSN: 0002-9394 ISO Abbreviation: Am. J. Ophthalmol. Publication Date: 2003 Sep |
Date Detail:
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Created Date: 2003-09-11 Completed Date: 2003-09-22 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0370500 Medline TA: Am J Ophthalmol Country: United States |
Other Details:
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Languages: eng Pagination: 433-41 Citation Subset: AIM; IM |
Affiliation:
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Division of Endocrinology, Diabetes, Metabolism, Nutrition and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Decompression, Surgical* Female Follow-Up Studies Graves Disease / complications, physiopathology, surgery* Humans Male Middle Aged Ophthalmoscopy Optic Nerve Diseases / etiology, physiopathology, surgery* Patient Satisfaction Questionnaires Retrospective Studies Treatment Outcome Visual Acuity Visual Fields |
| Grant Support | |
ID/Acronym/Agency:
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EY 08039/EY/NEI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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