Document Detail

Optic neuropathy of Graves disease: results of transantral orbital decompression and long-term follow-up in 215 patients.
MedLine Citation:
PMID:  12967795     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To review demographic characteristics, clinical features, and long-term outcomes of patients with optic neuropathy of Graves disease after transantral orbital decompression. DESIGN: Retrospective analysis of noncomparative interventional case series; long-term follow-up by questionnaire. METHODS: Medical record data (preoperative and postoperative assessments) were collected from patients who had transantral orbital decompression to treat Graves optic neuropathy. Responses to two follow-up questionnaires concerning patient satisfaction were evaluated. Statistical analysis (reflected as P values) compared preoperative and early postoperative (< or =182 days) data. RESULTS: Between November 1969 and May 1989, 215 patients underwent transantral orbital decompression for Graves optic neuropathy. In 205 eyes with visual acuity of 20/40 or worse before decompression, visual acuity improved by 3 Snellen lines or more in 110 (54%) (P <.001). Of 291 eyes with visual field defects preoperatively, 120 (41%) had resolution, and 126 (43%) had improvement postoperatively (P <.001). Proptosis was reduced in 350 eyes by 4.4 +/- 2.3 mm (mean +/- SD) (P <.001). In 104 eyes, disk edema resolved in 72 (69%) and improved in 28 (27%). Responses to questionnaires mailed in 1990 and 2000 showed that 76% and 88% of respondents, respectively, were subjectively satisfied with the results of orbital decompression. CONCLUSIONS: Transantral orbital decompression appeared to be effective in treating optic neuropathy of Graves disease. Patient satisfaction was high at 10-year and 20-year follow-up.
Cacia V Soares-Welch; Vahab Fatourechi; George B Bartley; Charles W Beatty; Colum A Gorman; Rebecca S Bahn; Erik J Bergstralh; Cathy D Schleck; James A Garrity
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of ophthalmology     Volume:  136     ISSN:  0002-9394     ISO Abbreviation:  Am. J. Ophthalmol.     Publication Date:  2003 Sep 
Date Detail:
Created Date:  2003-09-11     Completed Date:  2003-09-22     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370500     Medline TA:  Am J Ophthalmol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  433-41     Citation Subset:  AIM; IM    
Division of Endocrinology, Diabetes, Metabolism, Nutrition and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA.
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MeSH Terms
Decompression, Surgical*
Follow-Up Studies
Graves Disease / complications,  physiopathology,  surgery*
Middle Aged
Optic Nerve Diseases / etiology,  physiopathology,  surgery*
Patient Satisfaction
Retrospective Studies
Treatment Outcome
Visual Acuity
Visual Fields
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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