Document Detail

Optic neuritis. Differential losses of luminance and chromatic function near a scotoma.
MedLine Citation:
PMID:  7922464     Owner:  NLM     Status:  MEDLINE    
Visual sensitivity to achromatic and chromatic stimulus flashes was determined at sites just inside, on the boundary and just outside scotomata in 11 patients with recovered optic neuritis. The colour of the flashes and the size of the steady background on which they appeared were such that detection was more likely to be mediated by either the large-diameter, magnocellular fibres or the small-diameter, parvocellular fibres of the anterior visual pathway. The spacing of the test sites ranged from 0.5 degrees to 4 degrees visual angle, depending on the shape and location of the scotomata. The greatest differences in sensitivity were between sites just inside and just outside the scotoma and in response to achromatic stimuli more likely to involve the magnocellular fibres. This effect may be due to the size of magnocellular fibres or to their relatively smaller numbers.
M L Phillips; D H Foster; W P Honan; G K Edgar; J R Heron
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Brain : a journal of neurology     Volume:  117 ( Pt 4)     ISSN:  0006-8950     ISO Abbreviation:  Brain     Publication Date:  1994 Aug 
Date Detail:
Created Date:  1994-10-27     Completed Date:  1994-10-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372537     Medline TA:  Brain     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  767-73     Citation Subset:  AIM; IM    
Department of Postgraduate Medicine, Keele University, Staffordshire, UK.
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MeSH Terms
Color Perception*
Demyelinating Diseases / physiopathology
Optic Nerve / physiopathology
Optic Neuritis / physiopathology*
Scotoma / physiopathology*
Sensory Thresholds
Visual Cortex / physiopathology
Visual Pathways

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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