| Optic nerve involvement with panuveitis in sweet syndrome. | |
| | |
MedLine Citation:
|
PMID: 21595532 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Purpose: To report a case of a patient with optic nerve involvement in neuro-Sweet syndrome and review the literature on this systemic disease. Methods: Interventional case report and review of the literature. Results: A 49-year-old man developed an acute exacerbation of bilateral panuveitis and optic disc edema together with symptoms of a papular rash on his forearms, fevers, malaise, and arthalgias. Laboratory findings revealed an aseptic meningitis and neutrophilic leukocytosis. Biopsy of the skin rash demonstrated an intense neutrophilic infiltrate in the dermis consistent with the diagnosis of neuro-Sweet syndrome. The patient continued to require corticosteroids for inflammation control in spite of immunomodulatory therapies, including tumor necrosis factor-alpha inhibitor infliximab. Conclusions: Sweet syndrome can present with optic nerve involvement. Screening for underlying etiologies, including autoimmune disease, malignancy, and offending drugs, is important for targeted therapy. |
| | |
Authors:
|
Ann-Marie Lobo; Rebecca Stacy; Dean Cestari; John H Stone; Frederick A Jakobiec; Lucia Sobrin |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Ocular immunology and inflammation Volume: 19 ISSN: 1744-5078 ISO Abbreviation: Ocul. Immunol. Inflamm. Publication Date: 2011 Jun |
Date Detail:
|
Created Date: 2011-05-20 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9312169 Medline TA: Ocul Immunol Inflamm Country: England |
Other Details:
|
Languages: eng Pagination: 167-70 Citation Subset: IM |
Affiliation:
|
Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Pigment dispersion syndrome masquerading as acute anterior uveitis.
Next Document: Review for disease of the year: differential diagnosis of ocular toxoplasmosis.