Document Detail


Optic nerve hypoplasia and growth hormone deficiency in a cholestatic infant.
MedLine Citation:
PMID:  16638511     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This report describes a 4-month-old male with cholestasis, hypoglycemia, and short stature. Symptoms appeared since neonatal age with jaundice, hypoglycemia, neurologic manifestations, and later with short stature. Laboratory investigation was indicative for cholestasis. Further research indicated isolated growth hormone deficiency with accompanying optic nerve hypoplasia. Unexplained hypoglycemia and cholestasis in neonates have to be investigated for growth hormone deficiency. Moreover, in cases with unexplained cholestasis, timely recognition of hypoglycemia is important for the early diagnosis of the disorder before the appearance of growth retardation.
Authors:
Ioannis Xinias; Maria Papadopoulou; Theodouli Papastavrou; Kaliopi Patsiaoura; Kleomenis Spiroglou
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric neurology     Volume:  34     ISSN:  0887-8994     ISO Abbreviation:  Pediatr. Neurol.     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-04-26     Completed Date:  2006-07-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8508183     Medline TA:  Pediatr Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  319-22     Citation Subset:  IM    
Affiliation:
Third Department of Paediatrics, Hippocration University Hospital, Thessaloniki, Greece.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Cholestasis / etiology*
Human Growth Hormone / deficiency*
Humans
Hypoglycemia / etiology*
Hypopituitarism / complications*,  congenital,  diagnosis*
Infant
Male
Optic Nerve / abnormalities*
Chemical
Reg. No./Substance:
12629-01-5/Human Growth Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Acute necrotizing encephalopathy associated with hemophagocytic syndrome.
Next Document:  Antiepileptic drugs: a case report in a pregnancy with a neural tube defect.