| Optic nerve head blood flow using a laser Doppler velocimeter and haemorheology in primary open angle glaucoma and normal pressure glaucoma. | |
| | |
MedLine Citation:
|
PMID: 8060927 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Optic disc blood flow velocity was measured in healthy patients, those with primary open angle glaucoma (POAG), and patients with normal pressure glaucoma (NPG). The velocity of the red blood cells (RBCs) in the capillaries of the optic nerve head (ONH) has been measured with a laser Doppler velocimeter (LDV), and blood viscosity has been evaluated notably by determining the aggregability of the RBCs with an erythroaggregameter. Our results in POAG patients and NPG patients showed that their optic nerve blood flow velocity was reduced and that the aggregability of the RBCs was increased. The hyperaggregability of the erythrocytes is responsible for the increase of the local viscosity in the papillary capillary network. These haemodynamic modifications observed in patients with glaucoma support the hypothesis of a vasogenic mechanism that could impair the optic nerve in glaucoma patients. |
| | |
Authors:
|
P Hamard; H Hamard; J Dufaux; S Quesnot |
Related Documents
:
|
14751857 - Red blood cell dysfunction in septic glucose-6-phosphate dehydrogenase-deficient mice. 21077907 - Susceptibility to hyperosmotic stress-induced phosphatidylserine exposure increases dur... 12365857 - Failure of pentoxifylline or cilostazol to improve blood and plasma viscosity, fibrinog... 19502557 - Peculiar flow patterns of rbcs suspended in viscous fluids and perfused through a narro... 1890477 - Readjustment of hematocrit values after packed red cell transfusion in the neonate. 14991667 - Studies on acute human infections using ftir microspectroscopy and cluster analysis. |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: The British journal of ophthalmology Volume: 78 ISSN: 0007-1161 ISO Abbreviation: Br J Ophthalmol Publication Date: 1994 Jun |
Date Detail:
|
Created Date: 1994-09-19 Completed Date: 1994-09-19 Revised Date: 2009-11-18 |
Medline Journal Info:
|
Nlm Unique ID: 0421041 Medline TA: Br J Ophthalmol Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 449-53 Citation Subset: IM |
Affiliation:
|
Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, Paris, France. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Blood Flow Velocity Blood Viscosity / physiology Erythrocyte Aggregation / physiology Female Glaucoma / blood, physiopathology* Glaucoma, Open-Angle / blood, physiopathology Hemorheology* Humans Intraocular Pressure / physiology Laser-Doppler Flowmetry* Male Middle Aged Optic Nerve / blood supply* Regional Blood Flow |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Evidence for a new role of natriuretic peptides: control of intraocular pressure.
Next Document: Excimer laser superficial keratectomy for proud nebulae in keratoconus.