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Optic Neuropathy Following Orbital Irradiation for Graves' Ophthalmopathy: A Case Report and Literature Review.
MedLine Citation:
PMID:  22029640     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Radiation optic neuropathy (RON) is a devastating complication of radiotherapy to the anterior visual pathway resulting in acute, profound and sometimes irreversible visual loss. Cumulative doses of radiation that exceed 50 Gy or radiation fractions of greater than 2 Gy are usually required for RON to develop. Several factors, such as diabetes and pre-existing compression of the optic nerve, are associated with a higher risk for developing RON at lower doses of radiation. We report a case of presumed subacute RON following orbital irradiation for Graves' ophthalmopathy, successfully treated with megadoses of intravenous corticosteroids.
Authors:
Margarita Sánchez-Orgaz; Anna Grabowska; Arantza Royo-Oreja; Mónica Asencio-Durán; Ricardo Romero-Martín; Alvaro Arbizu-Duralde
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-10-26
Journal Detail:
Title:  Orbit (Amsterdam, Netherlands)     Volume:  -     ISSN:  1744-5108     ISO Abbreviation:  -     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8301221     Medline TA:  Orbit     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Ophthalmology Service , Madrid , Spain.
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