| Optic neuritis. | |
| | |
MedLine Citation:
|
PMID: 20637989 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Optic neuritis usually presents with painful monocular vision loss in younger patients. Spontaneous improvement in vision occurs over weeks, and treatment with high-dose intravenous steroids increases the rate but not extent of visual recovery. Risk of progression to multiple sclerosis (MS) is largely dictated by baseline brain magnetic resonance imaging (MRI). Those with a normal MRI finding at the time of optic neuritis diagnosis have a lower rate of progression to multiple sclerosis than those with T2 hyperintense white matter lesions on MRI. High-dose intravenous steroids should be considered acutely in optic neuritis, and disease-modifying therapy should be considered in patients at high risk of MS as defined by MRI. |
| | |
Authors:
|
David Clark; Workayehu Kebede; Eric Eggenberger |
Related Documents
:
|
7871989 - Consecutive cerebral mri findings of acute relapsing disseminated encephalomyelitis. 10467389 - Mri in multiple sclerosis: correlation with expanded disability status scale (edss). 15355009 - Preoperative magnetic source imaging for brain tumor surgery: a quantitative comparison... 15293279 - Role of magnetic resonance imaging within diagnostic criteria for multiple sclerosis. 9664849 - A comparison between the sensitivities of 3-mm and 5-mm thick serial brain mri for dete... 10552239 - Multiple sclerosis: interobserver agreement in reporting active lesions on serial brain... 19597719 - Symptoms of pelvic floor dysfunction are poorly correlated with findings on clinical ex... 9391729 - Neural networks for the analysis of small pulmonary nodules. 7769939 - Preoperative identification of benign versus malignant parotid masses: a comparative st... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Neurologic clinics Volume: 28 ISSN: 1557-9875 ISO Abbreviation: Neurol Clin Publication Date: 2010 Aug |
Date Detail:
|
Created Date: 2010-07-19 Completed Date: 2010-10-28 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8219232 Medline TA: Neurol Clin Country: United States |
Other Details:
|
Languages: eng Pagination: 573-80 Citation Subset: IM |
Copyright Information:
|
Copyright 2010 Elsevier Inc. All rights reserved. |
Affiliation:
|
Department of Neurology and Ophthalmology, Michigan State University, A217 Clinical Center, 138 Service Road, East Lansing, MI 48824, USA. david.clark@hc.msu.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Administration, Oral Anti-Inflammatory Agents / administration & dosage Frontal Lobe / pathology Humans Magnetic Resonance Imaging / methods Multiple Sclerosis / complications Optic Nerve / pathology Optic Neuritis / diagnosis*, epidemiology, etiology, therapy* Prednisone / administration & dosage |
| Chemical | |
Reg. No./Substance:
|
0/Anti-Inflammatory Agents; 53-03-2/Prednisone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Preface.
Next Document: Giant Cell Arteritis.